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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFR2 All Species: 20.91
Human Site: T341 Identified Species: 41.82
UniProt: Q9UP52 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UP52 NP_003218.2 801 88755 T341 G F P S F N Q T Q F P P V A S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113151 672 74384 N237 C P Y S A I G N V T G E L V Y
Dog Lupus familis XP_546952 806 88711 T341 G F P S F N Q T Q F P P V Q S
Cat Felis silvestris
Mouse Mus musculus Q9JKX3 798 88384 T336 G F P S F N Q T Q F P P V E S
Rat Rattus norvegicus B2GUY2 798 88309 T336 G F P S F N Q T Q F P P V E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516658 498 55112 P63 P S K S S G L P N I P A Q T I
Chicken Gallus gallus Q90997 776 85640 T328 G F P S F N H T Q F P P V E S
Frog Xenopus laevis NP_001089576 754 85283 L294 E A D E G V G L P S I P V H P
Zebra Danio Brachydanio rerio NP_001009916 783 85895 T328 G F P S F N H T Q F P S T Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91406 770 85483 G299 I E E A K E D G V L P S I P V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M1S8 705 77149 T270 S L D D E L V T R R F P K I P
Baker's Yeast Sacchar. cerevisiae P47161 811 91999 D352 G Y P S K D S D T E H M S P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 81.9 87 N.A. 84.5 83.5 N.A. 32 38.8 26.8 49.8 N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: 100 N.A. 82.6 91.8 N.A. 89.8 89.5 N.A. 44.8 55.5 46.4 65 N.A. N.A. N.A. 41.4 N.A.
P-Site Identity: 100 N.A. 6.6 93.3 N.A. 93.3 93.3 N.A. 13.3 86.6 13.3 73.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. 13.3 93.3 N.A. 93.3 93.3 N.A. 13.3 86.6 13.3 73.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. 40.5 39.7 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 9 0 0 0 0 0 0 9 0 9 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 17 9 0 9 9 9 0 0 0 0 0 0 0 % D
% Glu: 9 9 9 9 9 9 0 0 0 9 0 9 0 25 0 % E
% Phe: 0 50 0 0 50 0 0 0 0 50 9 0 0 0 0 % F
% Gly: 59 0 0 0 9 9 17 9 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 17 0 0 0 9 0 0 9 0 % H
% Ile: 9 0 0 0 0 9 0 0 0 9 9 0 9 9 9 % I
% Lys: 0 0 9 0 17 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 0 9 0 0 0 9 9 9 0 9 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 50 0 9 9 0 0 0 0 0 0 % N
% Pro: 9 9 59 0 0 0 0 9 9 0 67 59 0 17 17 % P
% Gln: 0 0 0 0 0 0 34 0 50 0 0 0 9 17 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % R
% Ser: 9 9 0 75 9 0 9 0 0 9 0 17 9 0 50 % S
% Thr: 0 0 0 0 0 0 0 59 9 9 0 0 9 9 0 % T
% Val: 0 0 0 0 0 9 9 0 17 0 0 0 50 9 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _