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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS8
All Species:
21.82
Human Site:
T500
Identified Species:
60
UniProt:
Q9UP79
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP79
NP_008968
890
96672
T500
S
L
P
W
A
D
G
T
P
C
G
P
G
H
L
Chimpanzee
Pan troglodytes
XP_522252
888
96353
T498
S
L
P
W
A
D
G
T
P
C
R
P
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001112387
958
103619
T568
S
L
P
W
A
D
G
T
P
C
G
P
G
H
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P57110
905
98861
T515
S
L
L
W
A
D
G
T
P
C
G
P
G
H
L
Rat
Rattus norvegicus
Q9WUQ1
967
105687
T532
H
F
P
W
A
D
G
T
S
C
G
E
G
K
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507767
694
76466
K325
Q
E
E
V
V
K
P
K
P
L
V
N
G
N
W
Chicken
Gallus gallus
XP_001232457
748
82577
S379
G
Q
R
T
R
Y
Q
S
C
H
T
E
D
F
P
Frog
Xenopus laevis
NP_001088627
928
102191
T482
H
F
P
W
A
D
G
T
S
C
G
E
G
K
W
Zebra Danio
Brachydanio rerio
XP_001341878
927
103077
T482
S
L
P
W
A
D
G
T
S
C
G
T
N
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
86.5
N.A.
N.A.
79.5
46.4
N.A.
61.6
60.7
46.9
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
88.1
N.A.
N.A.
87.7
62
N.A.
68.4
69.6
63.4
63.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
N.A.
N.A.
93.3
60
N.A.
13.3
0
60
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
N.A.
N.A.
93.3
60
N.A.
20
6.6
60
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
78
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
78
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
78
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
12
12
0
0
0
0
0
0
0
0
34
0
0
0
% E
% Phe:
0
23
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
12
0
0
0
0
0
78
0
0
0
67
0
78
0
0
% G
% His:
23
0
0
0
0
0
0
0
0
12
0
0
0
45
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
12
0
0
0
0
0
23
0
% K
% Leu:
0
56
12
0
0
0
0
0
0
12
0
0
0
0
45
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
12
12
0
% N
% Pro:
0
0
67
0
0
0
12
0
56
0
0
45
0
0
12
% P
% Gln:
12
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
12
0
0
0
0
0
12
0
0
12
0
% R
% Ser:
56
0
0
0
0
0
0
12
34
0
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
78
0
0
12
12
0
0
12
% T
% Val:
0
0
0
12
12
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
78
0
0
0
0
0
0
0
0
0
0
34
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _