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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COG5 All Species: 15.76
Human Site: S315 Identified Species: 24.76
UniProt: Q9UP83 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UP83 NP_006339.3 839 92719 S315 V R G G P G R S T M P T P G N
Chimpanzee Pan troglodytes XP_001163243 839 92761 S315 V R G G P G R S T M P T P G N
Rhesus Macaque Macaca mulatta XP_001091632 839 93187 S315 I R G G P G R S T M P T P G N
Dog Lupus familis XP_540384 915 100544 S370 V R G G P G R S T M P T P G N
Cat Felis silvestris
Mouse Mus musculus Q8C0L8 829 91582 A284 V R G G P G R A A M P T P G S
Rat Rattus norvegicus XP_001076141 873 96086 A328 A R G G P G R A T M P T P G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509241 830 91568 R284 V R G S G P G R A T M P T P G
Chicken Gallus gallus XP_415949 817 90713 A272 T R G G P G R A A M P T P G N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038609 810 89826 M268 G A P G R A V M P T P G N T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJD3 751 84935 T265 P G K T P Q L T T T Q N F R A
Honey Bee Apis mellifera XP_624919 536 60039 L51 V L A N H E D L L S Q A T W V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795770 559 62030 I74 L L S Q A T G I E T L D G V L
Poplar Tree Populus trichocarpa XP_002302138 844 92630 G324 F G P G G I R G S G T P H I G
Maize Zea mays NP_001169223 818 89889 R297 G G P G G V Q R S G T P Q I G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176960 832 91633 S309 F G P G G I R S S G S P H I G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 95.9 85.6 N.A. 86.2 84.5 N.A. 83.5 82.5 N.A. 74.2 N.A. 25.6 28.7 N.A. 41
Protein Similarity: 100 99.7 97.5 88.4 N.A. 90.6 89.3 N.A. 89.6 88.4 N.A. 84.1 N.A. 44.9 43.3 N.A. 53.5
P-Site Identity: 100 100 93.3 100 N.A. 80 86.6 N.A. 20 80 N.A. 13.3 N.A. 13.3 6.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 20 86.6 N.A. 13.3 N.A. 20 6.6 N.A. 6.6
Percent
Protein Identity: 28.3 24.2 N.A. 27.7 N.A. N.A.
Protein Similarity: 48.7 45.4 N.A. 49.7 N.A. N.A.
P-Site Identity: 13.3 6.6 N.A. 20 N.A. N.A.
P-Site Similarity: 20 20 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 7 7 0 20 20 0 0 7 0 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % D
% Glu: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % E
% Phe: 14 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 14 27 54 74 27 47 14 7 0 20 0 7 7 47 27 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 14 0 0 % H
% Ile: 7 0 0 0 0 14 0 7 0 0 0 0 0 20 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 14 0 0 0 0 7 7 7 0 7 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 7 0 47 7 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 0 7 7 0 40 % N
% Pro: 7 0 27 0 54 7 0 0 7 0 54 27 47 7 0 % P
% Gln: 0 0 0 7 0 7 7 0 0 0 14 0 7 0 0 % Q
% Arg: 0 54 0 0 7 0 60 14 0 0 0 0 0 7 0 % R
% Ser: 0 0 7 7 0 0 0 34 20 7 7 0 0 0 7 % S
% Thr: 7 0 0 7 0 7 0 7 40 27 14 47 14 7 0 % T
% Val: 40 0 0 0 0 7 7 0 0 0 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _