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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG5
All Species:
36.36
Human Site:
S491
Identified Species:
57.14
UniProt:
Q9UP83
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP83
NP_006339.3
839
92719
S491
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Chimpanzee
Pan troglodytes
XP_001163243
839
92761
S491
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Rhesus Macaque
Macaca mulatta
XP_001091632
839
93187
S491
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Dog
Lupus familis
XP_540384
915
100544
S546
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0L8
829
91582
S460
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Rat
Rattus norvegicus
XP_001076141
873
96086
S504
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509241
830
91568
S461
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Chicken
Gallus gallus
XP_415949
817
90713
S448
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038609
810
89826
S441
A
Y
L
S
K
S
L
S
R
L
F
D
P
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJD3
751
84935
A426
I
D
S
R
L
T
N
A
I
A
N
V
F
A
A
Honey Bee
Apis mellifera
XP_624919
536
60039
I212
L
R
I
V
N
G
A
I
D
N
V
I
D
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795770
559
62030
K235
T
V
V
G
H
C
E
K
A
L
R
K
N
I
K
Poplar Tree
Populus trichocarpa
XP_002302138
844
92630
E497
R
G
S
V
P
S
K
E
Q
V
S
R
I
L
S
Maize
Zea mays
NP_001169223
818
89889
D470
R
G
T
I
P
S
K
D
Q
I
S
R
L
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176960
832
91633
E482
R
G
S
L
P
S
K
E
Q
I
S
Q
V
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.9
85.6
N.A.
86.2
84.5
N.A.
83.5
82.5
N.A.
74.2
N.A.
25.6
28.7
N.A.
41
Protein Similarity:
100
99.7
97.5
88.4
N.A.
90.6
89.3
N.A.
89.6
88.4
N.A.
84.1
N.A.
44.9
43.3
N.A.
53.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
13.3
6.6
N.A.
20
Percent
Protein Identity:
28.3
24.2
N.A.
27.7
N.A.
N.A.
Protein Similarity:
48.7
45.4
N.A.
49.7
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
0
0
0
7
7
7
7
0
0
0
7
14
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
7
7
0
0
60
7
0
0
% D
% Glu:
0
0
0
0
0
0
7
14
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
60
0
7
0
0
% F
% Gly:
0
20
0
7
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
7
0
0
0
7
7
14
0
7
7
67
0
% I
% Lys:
0
0
0
0
60
0
20
7
0
0
0
7
0
0
7
% K
% Leu:
7
0
60
7
7
0
60
0
0
67
0
0
7
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
7
7
0
7
0
60
% N
% Pro:
0
0
0
0
20
0
0
0
0
0
0
0
60
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
20
0
0
7
0
0
0
% Q
% Arg:
20
7
0
7
0
0
0
0
60
0
7
14
0
0
0
% R
% Ser:
0
0
20
60
0
80
0
60
0
0
20
0
0
0
20
% S
% Thr:
7
0
7
0
0
7
0
0
0
0
0
0
0
7
0
% T
% Val:
0
7
7
14
0
0
0
0
0
7
7
7
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _