Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COG5 All Species: 24.24
Human Site: S511 Identified Species: 38.1
UniProt: Q9UP83 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UP83 NP_006339.3 839 92719 S511 G G R N P P S S D E L D G I I
Chimpanzee Pan troglodytes XP_001163243 839 92761 S511 G G R N P P S S D E L D G I I
Rhesus Macaque Macaca mulatta XP_001091632 839 93187 S511 G G R N P P S S D E L D G I I
Dog Lupus familis XP_540384 915 100544 A566 G G R N P P S A D E L E G I I
Cat Felis silvestris
Mouse Mus musculus Q8C0L8 829 91582 S480 G G R N P P S S D E L D G I T
Rat Rattus norvegicus XP_001076141 873 96086 S524 G G R N P P S S D E L D G I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509241 830 91568 A481 G G R N P P S A D E L D G I I
Chicken Gallus gallus XP_415949 817 90713 S468 G G R N P P S S D E L D S I I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038609 810 89826 N461 G G R N P P S N D E L D S I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJD3 751 84935 L442 G K E L C T K L E A Q I K L G
Honey Bee Apis mellifera XP_624919 536 60039 T228 S E I E K I A T E S L D V T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795770 559 62030 S251 A L D V Q V L S H T T I P A G
Poplar Tree Populus trichocarpa XP_002302138 844 92630 V513 I Q E E V E A V Q L D G H L T
Maize Zea mays NP_001169223 818 89889 V486 I Q E E I E V V R T H G H L L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176960 832 91633 A502 I E A V H P D A R L T L L V L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 95.9 85.6 N.A. 86.2 84.5 N.A. 83.5 82.5 N.A. 74.2 N.A. 25.6 28.7 N.A. 41
Protein Similarity: 100 99.7 97.5 88.4 N.A. 90.6 89.3 N.A. 89.6 88.4 N.A. 84.1 N.A. 44.9 43.3 N.A. 53.5
P-Site Identity: 100 100 100 86.6 N.A. 93.3 100 N.A. 93.3 93.3 N.A. 86.6 N.A. 6.6 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 100 93.3 N.A. 93.3 N.A. 20 40 N.A. 6.6
Percent
Protein Identity: 28.3 24.2 N.A. 27.7 N.A. N.A.
Protein Similarity: 48.7 45.4 N.A. 49.7 N.A. N.A.
P-Site Identity: 0 0 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 13.3 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 14 20 0 7 0 0 0 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 7 0 60 0 7 60 0 0 0 % D
% Glu: 0 14 20 20 0 14 0 0 14 60 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 67 60 0 0 0 0 0 0 0 0 0 14 47 0 14 % G
% His: 0 0 0 0 7 0 0 0 7 0 7 0 14 0 0 % H
% Ile: 20 0 7 0 7 7 0 0 0 0 0 14 0 60 54 % I
% Lys: 0 7 0 0 7 0 7 0 0 0 0 0 7 0 0 % K
% Leu: 0 7 0 7 0 0 7 7 0 14 67 7 7 20 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 60 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 60 67 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 14 0 0 7 0 0 0 7 0 7 0 0 0 0 % Q
% Arg: 0 0 60 0 0 0 0 0 14 0 0 0 0 0 0 % R
% Ser: 7 0 0 0 0 0 60 47 0 7 0 0 14 0 0 % S
% Thr: 0 0 0 0 0 7 0 7 0 14 14 0 0 7 14 % T
% Val: 0 0 0 14 7 7 7 14 0 0 0 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _