Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COG5 All Species: 23.03
Human Site: S590 Identified Species: 36.19
UniProt: Q9UP83 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UP83 NP_006339.3 839 92719 S590 S L Y K L H Q S V T K A I H A
Chimpanzee Pan troglodytes XP_001163243 839 92761 S590 S L Y K L H Q S V T K A I H A
Rhesus Macaque Macaca mulatta XP_001091632 839 93187 S590 S L Y K L H Q S V T K A I H T
Dog Lupus familis XP_540384 915 100544 S645 S L Y K L H Q S I T K V V S S
Cat Felis silvestris
Mouse Mus musculus Q8C0L8 829 91582 S559 S L F K L H Q S V T K V V A S
Rat Rattus norvegicus XP_001076141 873 96086 S603 S L F K L H Q S V T K V V A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509241 830 91568 A560 S L F R W H Q A I V K V I S S
Chicken Gallus gallus XP_415949 817 90713 A547 S L Y K L H Q A V L K V V T N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038609 810 89826 A540 S L F R L Q Q A V A K V I S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJD3 751 84935 M521 G T I L Q Q I M E S I I T T I
Honey Bee Apis mellifera XP_624919 536 60039 W307 D E L S Q K F W N S V N C L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795770 559 62030 L330 D G H G N I M L S F W M S L T
Poplar Tree Populus trichocarpa XP_002302138 844 92630 S592 F L A A D V L S P S L G A I Y
Maize Zea mays NP_001169223 818 89889 S565 N V A S E V L S P S L G V V Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176960 832 91633 A581 D V L S P Y L A A I Y D A A C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 95.9 85.6 N.A. 86.2 84.5 N.A. 83.5 82.5 N.A. 74.2 N.A. 25.6 28.7 N.A. 41
Protein Similarity: 100 99.7 97.5 88.4 N.A. 90.6 89.3 N.A. 89.6 88.4 N.A. 84.1 N.A. 44.9 43.3 N.A. 53.5
P-Site Identity: 100 100 93.3 66.6 N.A. 66.6 66.6 N.A. 40 60 N.A. 46.6 N.A. 0 0 N.A. 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 73.3 73.3 N.A. 66.6 N.A. 6.6 6.6 N.A. 6.6
Percent
Protein Identity: 28.3 24.2 N.A. 27.7 N.A. N.A.
Protein Similarity: 48.7 45.4 N.A. 49.7 N.A. N.A.
P-Site Identity: 13.3 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 20 33.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 7 0 0 0 27 7 7 0 20 14 20 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % C
% Asp: 20 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % D
% Glu: 0 7 0 0 7 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 7 0 27 0 0 0 7 0 0 7 0 0 0 0 0 % F
% Gly: 7 7 0 7 0 0 0 0 0 0 0 14 0 0 7 % G
% His: 0 0 7 0 0 54 0 0 0 0 0 0 0 20 0 % H
% Ile: 0 0 7 0 0 7 7 0 14 7 7 7 34 7 7 % I
% Lys: 0 0 0 47 0 7 0 0 0 0 60 0 0 0 0 % K
% Leu: 0 67 14 7 54 0 20 7 0 7 14 0 0 14 7 % L
% Met: 0 0 0 0 0 0 7 7 0 0 0 7 0 0 0 % M
% Asn: 7 0 0 0 7 0 0 0 7 0 0 7 0 0 7 % N
% Pro: 0 0 0 0 7 0 0 0 14 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 14 14 60 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 60 0 0 20 0 0 0 54 7 27 0 0 7 20 27 % S
% Thr: 0 7 0 0 0 0 0 0 0 40 0 0 7 14 14 % T
% Val: 0 14 0 0 0 14 0 0 47 7 7 40 34 7 0 % V
% Trp: 0 0 0 0 7 0 0 7 0 0 7 0 0 0 0 % W
% Tyr: 0 0 34 0 0 7 0 0 0 0 7 0 0 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _