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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG5
All Species:
34.24
Human Site:
S627
Identified Species:
53.81
UniProt:
Q9UP83
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP83
NP_006339.3
839
92719
S627
T
M
H
Q
E
D
F
S
G
S
L
S
S
S
G
Chimpanzee
Pan troglodytes
XP_001163243
839
92761
S627
T
M
H
Q
E
D
F
S
G
S
L
S
S
S
G
Rhesus Macaque
Macaca mulatta
XP_001091632
839
93187
S627
T
M
H
Q
E
D
F
S
G
S
L
S
S
S
G
Dog
Lupus familis
XP_540384
915
100544
S703
T
M
H
Q
E
D
F
S
G
S
I
S
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0L8
829
91582
S617
T
M
H
Q
E
D
F
S
G
A
S
S
S
S
G
Rat
Rattus norvegicus
XP_001076141
873
96086
S661
T
V
H
Q
E
D
F
S
G
S
L
T
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509241
830
91568
S618
T
M
H
Q
E
D
F
S
G
S
V
S
G
P
G
Chicken
Gallus gallus
XP_415949
817
90713
S605
T
M
H
Q
E
D
F
S
G
S
L
S
S
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038609
810
89826
S598
T
M
H
Q
E
D
F
S
S
P
L
P
A
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJD3
751
84935
E557
G
P
S
M
Y
M
K
E
L
Q
E
F
V
N
R
Honey Bee
Apis mellifera
XP_624919
536
60039
F343
Y
P
K
F
L
R
I
F
L
D
L
R
K
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795770
559
62030
L366
E
G
E
Y
P
K
L
L
R
L
Y
N
D
L
W
Poplar Tree
Populus trichocarpa
XP_002302138
844
92630
G630
Q
I
H
D
H
N
F
G
A
H
G
M
D
A
A
Maize
Zea mays
NP_001169223
818
89889
A603
K
M
H
E
Q
D
F
A
G
Q
G
M
D
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176960
832
91633
D622
G
A
D
D
A
D
M
D
N
N
A
S
S
Y
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.9
85.6
N.A.
86.2
84.5
N.A.
83.5
82.5
N.A.
74.2
N.A.
25.6
28.7
N.A.
41
Protein Similarity:
100
99.7
97.5
88.4
N.A.
90.6
89.3
N.A.
89.6
88.4
N.A.
84.1
N.A.
44.9
43.3
N.A.
53.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
100
N.A.
66.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
86.6
100
N.A.
73.3
N.A.
6.6
6.6
N.A.
6.6
Percent
Protein Identity:
28.3
24.2
N.A.
27.7
N.A.
N.A.
Protein Similarity:
48.7
45.4
N.A.
49.7
N.A.
N.A.
P-Site Identity:
13.3
33.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
33.3
60
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
0
7
7
7
7
0
7
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
14
0
74
0
7
0
7
0
0
20
0
0
% D
% Glu:
7
0
7
7
60
0
0
7
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
74
7
0
0
0
7
0
0
0
% F
% Gly:
14
7
0
0
0
0
0
7
60
0
14
0
7
7
60
% G
% His:
0
0
74
0
7
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
7
0
7
0
0
7
7
0
0
0
0
0
7
0
0
% K
% Leu:
0
0
0
0
7
0
7
7
14
7
47
0
0
7
7
% L
% Met:
0
60
0
7
0
7
7
0
0
0
0
14
0
0
7
% M
% Asn:
0
0
0
0
0
7
0
0
7
7
0
7
0
7
0
% N
% Pro:
0
14
0
0
7
0
0
0
0
7
0
7
0
7
0
% P
% Gln:
7
0
0
60
7
0
0
0
0
14
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
7
0
0
7
0
7
7
% R
% Ser:
0
0
7
0
0
0
0
60
7
47
7
54
54
47
7
% S
% Thr:
60
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
0
0
7
7
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _