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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COG5 All Species: 31.52
Human Site: S811 Identified Species: 49.52
UniProt: Q9UP83 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UP83 NP_006339.3 839 92719 S811 A L E A Y V Q S V R S R E G K
Chimpanzee Pan troglodytes XP_001163243 839 92761 S811 A L E A Y V Q S V R S R E G K
Rhesus Macaque Macaca mulatta XP_001091632 839 93187 S811 A L E A Y V Q S V R S R E G K
Dog Lupus familis XP_540384 915 100544 S887 A L E A Y V Q S V R S R E G K
Cat Felis silvestris
Mouse Mus musculus Q8C0L8 829 91582 S801 A L E A Y V Q S V R S R D G K
Rat Rattus norvegicus XP_001076141 873 96086 S845 A L E A Y V Q S V R G R E G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509241 830 91568 S802 A L E A Y V Q S V R T R E G K
Chicken Gallus gallus XP_415949 817 90713 S789 A L E A Y V Q S V R A R E G K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038609 810 89826 Q782 G A L E A Y V Q S V R A R Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJD3 751 84935 N723 A L Q R Y R D N A R R K N I Q
Honey Bee Apis mellifera XP_624919 536 60039 N509 E I D L L T K N I L S P L L A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795770 559 62030 H532 V N S L Y Q F H R A I S K V T
Poplar Tree Populus trichocarpa XP_002302138 844 92630 D816 G I K A T L D D Y A A K I R S
Maize Zea mays NP_001169223 818 89889 V791 L D D Y E M R V R S R G D K E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176960 832 91633 I805 L D D Y A V K I R S R G D K E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 95.9 85.6 N.A. 86.2 84.5 N.A. 83.5 82.5 N.A. 74.2 N.A. 25.6 28.7 N.A. 41
Protein Similarity: 100 99.7 97.5 88.4 N.A. 90.6 89.3 N.A. 89.6 88.4 N.A. 84.1 N.A. 44.9 43.3 N.A. 53.5
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 93.3 N.A. 0 N.A. 26.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 100 N.A. 0 N.A. 53.3 40 N.A. 13.3
Percent
Protein Identity: 28.3 24.2 N.A. 27.7 N.A. N.A.
Protein Similarity: 48.7 45.4 N.A. 49.7 N.A. N.A.
P-Site Identity: 6.6 0 N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 7 0 60 14 0 0 0 7 14 14 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 20 0 0 0 14 7 0 0 0 0 20 0 0 % D
% Glu: 7 0 54 7 7 0 0 0 0 0 0 0 47 0 14 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 14 0 0 0 0 0 0 0 0 0 7 14 0 54 7 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 14 0 0 0 0 0 7 7 0 7 0 7 7 0 % I
% Lys: 0 0 7 0 0 0 14 0 0 0 0 14 7 14 54 % K
% Leu: 14 60 7 14 7 7 0 0 0 7 0 0 7 7 0 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 14 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 0 7 0 0 7 54 7 0 0 0 0 0 7 7 % Q
% Arg: 0 0 0 7 0 7 7 0 20 60 27 54 7 7 0 % R
% Ser: 0 0 7 0 0 0 0 54 7 14 40 7 0 0 7 % S
% Thr: 0 0 0 0 7 7 0 0 0 0 7 0 0 0 7 % T
% Val: 7 0 0 0 0 60 7 7 54 7 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 14 67 7 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _