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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG5
All Species:
24.24
Human Site:
T122
Identified Species:
38.1
UniProt:
Q9UP83
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP83
NP_006339.3
839
92719
T122
E
D
L
L
A
Q
A
T
G
I
E
S
L
E
G
Chimpanzee
Pan troglodytes
XP_001163243
839
92761
T122
E
D
L
L
A
Q
A
T
G
I
E
S
L
E
G
Rhesus Macaque
Macaca mulatta
XP_001091632
839
93187
T122
E
D
L
L
A
Q
A
T
G
I
E
S
L
E
G
Dog
Lupus familis
XP_540384
915
100544
T177
E
D
L
L
A
Q
A
T
G
I
E
S
L
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0L8
829
91582
G112
T
R
I
G
A
L
Q
G
A
V
D
R
M
K
S
Rat
Rattus norvegicus
XP_001076141
873
96086
T135
E
D
L
L
A
Q
A
T
G
I
E
S
L
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509241
830
91568
G112
T
R
I
G
A
L
Q
G
A
V
D
R
I
R
V
Chicken
Gallus gallus
XP_415949
817
90713
A107
S
T
V
D
R
I
R
A
K
I
V
D
P
Y
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038609
810
89826
V106
D
R
I
R
T
K
I
V
D
P
Y
N
K
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJD3
751
84935
E103
D
T
Q
Y
Q
Q
V
E
N
Q
T
Q
V
L
G
Honey Bee
Apis mellifera
XP_624919
536
60039
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795770
559
62030
Poplar Tree
Populus trichocarpa
XP_002302138
844
92630
S126
S
H
L
L
H
Q
L
S
S
L
K
D
A
E
L
Maize
Zea mays
NP_001169223
818
89889
S120
A
S
L
S
S
L
P
S
H
L
N
L
L
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176960
832
91633
S113
P
E
L
L
A
Q
L
S
S
L
S
H
A
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.9
85.6
N.A.
86.2
84.5
N.A.
83.5
82.5
N.A.
74.2
N.A.
25.6
28.7
N.A.
41
Protein Similarity:
100
99.7
97.5
88.4
N.A.
90.6
89.3
N.A.
89.6
88.4
N.A.
84.1
N.A.
44.9
43.3
N.A.
53.5
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
6.6
6.6
N.A.
0
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
40
100
N.A.
33.3
13.3
N.A.
26.6
N.A.
26.6
0
N.A.
0
Percent
Protein Identity:
28.3
24.2
N.A.
27.7
N.A.
N.A.
Protein Similarity:
48.7
45.4
N.A.
49.7
N.A.
N.A.
P-Site Identity:
26.6
13.3
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
46.6
33.3
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
54
0
34
7
14
0
0
0
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
34
0
7
0
0
0
0
7
0
14
14
0
7
0
% D
% Glu:
34
7
0
0
0
0
0
7
0
0
34
0
0
40
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
14
0
0
0
14
34
0
0
0
0
0
40
% G
% His:
0
7
0
0
7
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
0
0
20
0
0
7
7
0
0
40
0
0
7
7
0
% I
% Lys:
0
0
0
0
0
7
0
0
7
0
7
0
7
7
0
% K
% Leu:
0
0
54
47
0
20
14
0
0
20
0
7
40
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
7
7
0
0
7
% N
% Pro:
7
0
0
0
0
0
7
0
0
7
0
0
7
0
0
% P
% Gln:
0
0
7
0
7
54
14
0
0
7
0
7
0
0
0
% Q
% Arg:
0
20
0
7
7
0
7
0
0
0
0
14
0
7
0
% R
% Ser:
14
7
0
7
7
0
0
20
14
0
7
34
0
7
14
% S
% Thr:
14
14
0
0
7
0
0
34
0
0
7
0
0
0
0
% T
% Val:
0
0
7
0
0
0
7
7
0
14
7
0
7
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _