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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG5
All Species:
35.45
Human Site:
Y643
Identified Species:
55.71
UniProt:
Q9UP83
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP83
NP_006339.3
839
92719
Y643
P
D
V
P
C
S
L
Y
M
K
E
L
Q
G
F
Chimpanzee
Pan troglodytes
XP_001163243
839
92761
Y643
P
D
V
P
C
S
L
Y
M
K
E
L
Q
G
F
Rhesus Macaque
Macaca mulatta
XP_001091632
839
93187
Y643
P
D
V
P
C
S
L
Y
M
K
E
L
Q
G
F
Dog
Lupus familis
XP_540384
915
100544
Y719
P
D
V
P
C
S
L
Y
M
K
E
L
Q
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0L8
829
91582
Y633
P
D
V
P
C
S
L
Y
M
K
E
L
Q
G
F
Rat
Rattus norvegicus
XP_001076141
873
96086
Y677
P
D
V
P
C
S
L
Y
M
K
E
L
Q
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509241
830
91568
Y634
S
A
T
P
C
S
L
Y
M
K
E
L
Q
G
F
Chicken
Gallus gallus
XP_415949
817
90713
Y621
P
D
V
P
C
S
L
Y
M
K
E
L
Q
G
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038609
810
89826
Y614
P
D
V
P
C
S
L
Y
M
R
E
L
Q
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJD3
751
84935
F573
W
S
H
H
I
A
L
F
D
D
K
Q
M
T
K
Honey Bee
Apis mellifera
XP_624919
536
60039
I359
E
R
S
Q
S
I
G
I
Y
K
I
N
H
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795770
559
62030
I382
R
L
E
Q
F
N
I
I
S
V
A
V
S
S
V
Poplar Tree
Populus trichocarpa
XP_002302138
844
92630
M646
D
N
N
A
S
P
Y
M
E
D
L
Q
K
C
I
Maize
Zea mays
NP_001169223
818
89889
M619
D
N
N
A
S
A
Y
M
E
E
L
Q
K
C
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176960
832
91633
H638
E
L
Q
R
S
I
L
H
F
R
K
E
F
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.9
85.6
N.A.
86.2
84.5
N.A.
83.5
82.5
N.A.
74.2
N.A.
25.6
28.7
N.A.
41
Protein Similarity:
100
99.7
97.5
88.4
N.A.
90.6
89.3
N.A.
89.6
88.4
N.A.
84.1
N.A.
44.9
43.3
N.A.
53.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
100
N.A.
93.3
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
100
N.A.
100
N.A.
26.6
6.6
N.A.
20
Percent
Protein Identity:
28.3
24.2
N.A.
27.7
N.A.
N.A.
Protein Similarity:
48.7
45.4
N.A.
49.7
N.A.
N.A.
P-Site Identity:
0
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
14
0
14
0
0
0
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
60
0
0
0
0
0
0
0
0
14
0
% C
% Asp:
14
54
0
0
0
0
0
0
7
14
0
0
0
7
0
% D
% Glu:
14
0
7
0
0
0
0
0
14
7
60
7
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
7
7
0
0
0
7
0
60
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
0
0
60
0
% G
% His:
0
0
7
7
0
0
0
7
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
7
14
7
14
0
0
7
0
0
0
14
% I
% Lys:
0
0
0
0
0
0
0
0
0
60
14
0
14
0
7
% K
% Leu:
0
14
0
0
0
0
74
0
0
0
14
60
0
7
0
% L
% Met:
0
0
0
0
0
0
0
14
60
0
0
0
7
0
0
% M
% Asn:
0
14
14
0
0
7
0
0
0
0
0
7
0
0
0
% N
% Pro:
54
0
0
60
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
14
0
0
0
0
0
0
0
20
60
0
0
% Q
% Arg:
7
7
0
7
0
0
0
0
0
14
0
0
0
0
0
% R
% Ser:
7
7
7
0
27
60
0
0
7
0
0
0
7
7
7
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
0
54
0
0
0
0
0
0
7
0
7
0
0
7
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
60
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _