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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPK3 All Species: 3.64
Human Site: S11 Identified Species: 6.67
UniProt: Q9UPE1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPE1 NP_055185 533 58997 S11 S T G G G G D S G G S G G S S
Chimpanzee Pan troglodytes XP_001160930 537 60598 E12 S E K S S S S E R P E P Q Q K
Rhesus Macaque Macaca mulatta XP_001088947 537 60682 E12 S E K S S S S E R P E P Q Q K
Dog Lupus familis XP_855347 537 59564 P20 T R G R C W S P E R V G F Q A
Cat Felis silvestris
Mouse Mus musculus Q9Z0G2 565 62346 V11 N A G G S G S V D C G G S S S
Rat Rattus norvegicus NP_908934 563 62152 M11 S A G G S G G M D C G G S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511138 531 59528 Q11 S S S S D S S Q A P C G R E E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694973 707 78272 S140 A P S L G L P S I L S S T P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649387 749 84628 L212 L T I R L P Q L A E P V K E E
Honey Bee Apis mellifera XP_001120563 589 66844 S56 T Q Q G Q G S S F Y Q D A S A
Nematode Worm Caenorhab. elegans Q03563 1003 112508 E354 K T E V N A N E E R L D D L S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002326404 560 63345 Q11 Q R R Q Q Q Q Q V K V E E E D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03656 742 83219 T90 S K T E D F S T K S I K K K P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.1 68.3 87.9 N.A. 89.7 89.6 N.A. 69.2 N.A. N.A. 57.8 N.A. 36.9 52.4 30.3 N.A.
Protein Similarity: 100 81.5 80.2 89.9 N.A. 91.1 90.9 N.A. 78.6 N.A. N.A. 65.7 N.A. 48.3 65 38.9 N.A.
P-Site Identity: 100 6.6 6.6 13.3 N.A. 40 46.6 N.A. 13.3 N.A. N.A. 20 N.A. 6.6 26.6 13.3 N.A.
P-Site Similarity: 100 6.6 6.6 26.6 N.A. 46.6 46.6 N.A. 20 N.A. N.A. 26.6 N.A. 6.6 40 20 N.A.
Percent
Protein Identity: 42.3 N.A. N.A. N.A. 32.3 N.A.
Protein Similarity: 56.6 N.A. N.A. N.A. 47 N.A.
P-Site Identity: 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 0 N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 0 0 8 0 0 16 0 0 0 8 0 16 % A
% Cys: 0 0 0 0 8 0 0 0 0 16 8 0 0 0 0 % C
% Asp: 0 0 0 0 16 0 8 0 16 0 0 16 8 0 8 % D
% Glu: 0 16 8 8 0 0 0 24 16 8 16 8 8 24 16 % E
% Phe: 0 0 0 0 0 8 0 0 8 0 0 0 8 0 0 % F
% Gly: 0 0 31 31 16 31 8 0 8 8 16 39 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 8 0 8 0 0 0 0 % I
% Lys: 8 8 16 0 0 0 0 0 8 8 0 8 16 8 16 % K
% Leu: 8 0 0 8 8 8 0 8 0 8 8 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 8 8 8 0 24 8 16 0 8 16 % P
% Gln: 8 8 8 8 16 8 16 16 0 0 8 0 16 24 0 % Q
% Arg: 0 16 8 16 0 0 0 0 16 16 0 0 8 0 0 % R
% Ser: 47 8 16 24 31 24 54 24 0 8 16 8 16 31 31 % S
% Thr: 16 24 8 0 0 0 0 8 0 0 0 0 8 0 0 % T
% Val: 0 0 0 8 0 0 0 8 8 0 16 8 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _