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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK3
All Species:
4.55
Human Site:
S19
Identified Species:
8.33
UniProt:
Q9UPE1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPE1
NP_055185
533
58997
S19
G
G
S
G
G
S
S
S
S
S
Q
A
S
C
G
Chimpanzee
Pan troglodytes
XP_001160930
537
60598
A20
R
P
E
P
Q
Q
K
A
P
L
V
P
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001088947
537
60682
A20
R
P
E
P
Q
Q
K
A
P
L
V
P
P
P
P
Dog
Lupus familis
XP_855347
537
59564
L28
E
R
V
G
F
Q
A
L
T
R
P
G
T
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0G2
565
62346
S19
D
C
G
G
S
S
S
S
S
Q
T
S
C
G
P
Rat
Rattus norvegicus
NP_908934
563
62152
S19
D
C
G
G
S
S
S
S
S
Q
T
S
C
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511138
531
59528
G19
A
P
C
G
R
E
E
G
S
P
L
P
P
T
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694973
707
78272
T148
I
L
S
S
T
P
P
T
P
Q
A
P
S
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649387
749
84628
E220
A
E
P
V
K
E
E
E
V
E
Y
I
E
L
K
Honey Bee
Apis mellifera
XP_001120563
589
66844
Q64
F
Y
Q
D
A
S
A
Q
R
P
Y
S
S
D
N
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
V362
E
R
L
D
D
L
S
V
S
P
G
R
S
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326404
560
63345
R19
V
K
V
E
E
E
D
R
S
S
S
S
D
S
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
D98
K
S
I
K
K
K
P
D
S
G
V
E
S
H
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.1
68.3
87.9
N.A.
89.7
89.6
N.A.
69.2
N.A.
N.A.
57.8
N.A.
36.9
52.4
30.3
N.A.
Protein Similarity:
100
81.5
80.2
89.9
N.A.
91.1
90.9
N.A.
78.6
N.A.
N.A.
65.7
N.A.
48.3
65
38.9
N.A.
P-Site Identity:
100
0
0
13.3
N.A.
33.3
33.3
N.A.
13.3
N.A.
N.A.
13.3
N.A.
0
13.3
20
N.A.
P-Site Similarity:
100
6.6
6.6
33.3
N.A.
40
40
N.A.
13.3
N.A.
N.A.
20
N.A.
0
26.6
20
N.A.
Percent
Protein Identity:
42.3
N.A.
N.A.
N.A.
32.3
N.A.
Protein Similarity:
56.6
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
8
0
16
16
0
0
8
8
0
0
0
% A
% Cys:
0
16
8
0
0
0
0
0
0
0
0
0
16
8
0
% C
% Asp:
16
0
0
16
8
0
8
8
0
0
0
0
8
16
0
% D
% Glu:
16
8
16
8
8
24
16
8
0
8
0
8
8
0
0
% E
% Phe:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
16
39
8
0
0
8
0
8
8
8
0
16
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
8
0
8
16
8
16
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
8
0
0
8
0
8
0
16
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
0
24
8
16
0
8
16
0
24
24
8
31
24
16
39
% P
% Gln:
0
0
8
0
16
24
0
8
0
24
8
0
0
0
8
% Q
% Arg:
16
16
0
0
8
0
0
8
8
8
0
8
0
0
0
% R
% Ser:
0
8
16
8
16
31
31
24
54
16
8
31
39
16
8
% S
% Thr:
0
0
0
0
8
0
0
8
8
0
16
0
8
8
0
% T
% Val:
8
0
16
8
0
0
0
8
8
0
24
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _