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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPK3 All Species: 1.21
Human Site: S21 Identified Species: 2.22
UniProt: Q9UPE1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPE1 NP_055185 533 58997 S21 S G G S S S S S Q A S C G P E
Chimpanzee Pan troglodytes XP_001160930 537 60598 L22 E P Q Q K A P L V P P P P P P
Rhesus Macaque Macaca mulatta XP_001088947 537 60682 L22 E P Q Q K A P L V P P P P P P
Dog Lupus familis XP_855347 537 59564 R30 V G F Q A L T R P G T S G G Y
Cat Felis silvestris
Mouse Mus musculus Q9Z0G2 565 62346 Q21 G G S S S S S Q T S C G P E S
Rat Rattus norvegicus NP_908934 563 62152 Q21 G G S S S S S Q T S C G P E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511138 531 59528 P21 C G R E E G S P L P P T P P T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694973 707 78272 Q150 S S T P P T P Q A P S N Q P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649387 749 84628 E222 P V K E E E V E Y I E L K S E
Honey Bee Apis mellifera XP_001120563 589 66844 P66 Q D A S A Q R P Y S S D N G N
Nematode Worm Caenorhab. elegans Q03563 1003 112508 P364 L D D L S V S P G R S D S P G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002326404 560 63345 S21 V E E E D R S S S S D S G D Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03656 742 83219 G100 I K K K P D S G V E S H V S I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.1 68.3 87.9 N.A. 89.7 89.6 N.A. 69.2 N.A. N.A. 57.8 N.A. 36.9 52.4 30.3 N.A.
Protein Similarity: 100 81.5 80.2 89.9 N.A. 91.1 90.9 N.A. 78.6 N.A. N.A. 65.7 N.A. 48.3 65 38.9 N.A.
P-Site Identity: 100 6.6 6.6 13.3 N.A. 33.3 33.3 N.A. 20 N.A. N.A. 20 N.A. 6.6 13.3 26.6 N.A.
P-Site Similarity: 100 13.3 13.3 33.3 N.A. 40 40 N.A. 20 N.A. N.A. 26.6 N.A. 6.6 26.6 26.6 N.A.
Percent
Protein Identity: 42.3 N.A. N.A. N.A. 32.3 N.A.
Protein Similarity: 56.6 N.A. N.A. N.A. 47 N.A.
P-Site Identity: 20 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 16 16 0 0 8 8 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 16 8 0 0 0 % C
% Asp: 0 16 8 0 8 8 0 0 0 0 8 16 0 8 0 % D
% Glu: 16 8 8 24 16 8 0 8 0 8 8 0 0 16 16 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 39 8 0 0 8 0 8 8 8 0 16 24 16 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % I
% Lys: 0 8 16 8 16 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 8 0 0 8 0 8 0 16 8 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 8 % N
% Pro: 8 16 0 8 16 0 24 24 8 31 24 16 39 47 16 % P
% Gln: 8 0 16 24 0 8 0 24 8 0 0 0 8 0 0 % Q
% Arg: 0 0 8 0 0 8 8 8 0 8 0 0 0 0 0 % R
% Ser: 16 8 16 31 31 24 54 16 8 31 39 16 8 16 16 % S
% Thr: 0 0 8 0 0 8 8 0 16 0 8 8 0 0 16 % T
% Val: 16 8 0 0 0 8 8 0 24 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _