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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK3
All Species:
23.64
Human Site:
S246
Identified Species:
43.33
UniProt:
Q9UPE1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPE1
NP_055185
533
58997
S246
Q
A
G
A
P
P
P
S
R
S
I
V
S
T
A
Chimpanzee
Pan troglodytes
XP_001160930
537
60598
S247
K
A
G
A
P
P
P
S
G
S
A
V
S
T
A
Rhesus Macaque
Macaca mulatta
XP_001088947
537
60682
S247
K
A
G
A
P
P
P
S
G
S
A
V
S
T
A
Dog
Lupus familis
XP_855347
537
59564
Q248
M
R
R
K
R
K
Q
Q
K
R
L
L
E
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0G2
565
62346
S245
Q
S
G
A
Q
P
P
S
R
S
T
V
S
T
A
Rat
Rattus norvegicus
NP_908934
563
62152
S245
Q
S
G
A
Q
P
P
S
R
S
T
V
S
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511138
531
59528
S238
Q
S
G
A
P
P
P
S
G
S
T
V
S
S
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694973
707
78272
S375
K
A
G
A
P
P
P
S
G
S
S
V
S
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649387
749
84628
F447
L
R
V
K
G
V
D
F
P
D
S
Y
I
S
S
Honey Bee
Apis mellifera
XP_001120563
589
66844
V291
S
L
G
M
K
L
P
V
S
L
I
S
T
A
P
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
G589
K
M
N
M
K
M
S
G
S
A
V
S
T
A
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326404
560
63345
G233
S
G
I
A
R
L
N
G
D
L
S
R
N
Q
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
Q328
K
R
E
A
K
R
L
Q
R
H
V
S
R
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.1
68.3
87.9
N.A.
89.7
89.6
N.A.
69.2
N.A.
N.A.
57.8
N.A.
36.9
52.4
30.3
N.A.
Protein Similarity:
100
81.5
80.2
89.9
N.A.
91.1
90.9
N.A.
78.6
N.A.
N.A.
65.7
N.A.
48.3
65
38.9
N.A.
P-Site Identity:
100
80
80
0
N.A.
80
80
N.A.
73.3
N.A.
N.A.
80
N.A.
0
20
0
N.A.
P-Site Similarity:
100
86.6
86.6
20
N.A.
86.6
86.6
N.A.
86.6
N.A.
N.A.
86.6
N.A.
13.3
26.6
26.6
N.A.
Percent
Protein Identity:
42.3
N.A.
N.A.
N.A.
32.3
N.A.
Protein Similarity:
56.6
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
70
0
0
0
0
0
8
16
0
0
16
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
8
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
62
0
8
0
0
16
31
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
16
0
8
0
0
% I
% Lys:
39
0
0
16
24
8
0
0
8
0
0
0
0
0
8
% K
% Leu:
8
8
0
0
0
16
8
0
0
16
8
8
0
0
0
% L
% Met:
8
8
0
16
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
39
54
62
0
8
0
0
0
0
0
16
% P
% Gln:
31
0
0
0
16
0
8
16
0
0
0
0
0
8
0
% Q
% Arg:
0
24
8
0
16
8
0
0
31
8
0
8
8
0
8
% R
% Ser:
16
24
0
0
0
0
8
54
16
54
24
24
54
24
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
24
0
16
47
0
% T
% Val:
0
0
8
0
0
8
0
8
0
0
16
54
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _