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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPK3 All Species: 5.45
Human Site: S303 Identified Species: 10
UniProt: Q9UPE1 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPE1 NP_055185 533 58997 S303 A A T Q A E D S G L R L D G G
Chimpanzee Pan troglodytes XP_001160930 537 60598 S304 P M T E A E R S G L H I R G G
Rhesus Macaque Macaca mulatta XP_001088947 537 60682 R307 H L K D K G P R T G G D A T K
Dog Lupus familis XP_855347 537 59564 A307 S P A S S S P A G G G E R S L
Cat Felis silvestris
Mouse Mus musculus Q9Z0G2 565 62346 V335 S P A S S S P V P G G E R S L
Rat Rattus norvegicus NP_908934 563 62152 P333 P A S S S P V P T G G E R S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511138 531 59528 P292 D I G T E R C P G V R L C H P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694973 707 78272 G478 W L E E S C N G Y G P L R F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649387 749 84628 T511 K E D T T T T T S S T L N S N
Honey Bee Apis mellifera XP_001120563 589 66844 Q335 L L K K Q M E Q I E E L E E Q
Nematode Worm Caenorhab. elegans Q03563 1003 112508 V664 N A S Q V E D V T M E D T V N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002326404 560 63345 N274 A L E E L S A N A K L N E G S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03656 742 83219 T455 N S V P H S V T R M F I N E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.1 68.3 87.9 N.A. 89.7 89.6 N.A. 69.2 N.A. N.A. 57.8 N.A. 36.9 52.4 30.3 N.A.
Protein Similarity: 100 81.5 80.2 89.9 N.A. 91.1 90.9 N.A. 78.6 N.A. N.A. 65.7 N.A. 48.3 65 38.9 N.A.
P-Site Identity: 100 53.3 0 6.6 N.A. 0 6.6 N.A. 20 N.A. N.A. 6.6 N.A. 6.6 6.6 26.6 N.A.
P-Site Similarity: 100 66.6 0 26.6 N.A. 13.3 20 N.A. 26.6 N.A. N.A. 26.6 N.A. 20 26.6 40 N.A.
Percent
Protein Identity: 42.3 N.A. N.A. N.A. 32.3 N.A.
Protein Similarity: 56.6 N.A. N.A. N.A. 47 N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 24 16 0 16 0 8 8 8 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % C
% Asp: 8 0 8 8 0 0 16 0 0 0 0 16 8 0 8 % D
% Glu: 0 8 16 24 8 24 8 0 0 8 16 24 16 16 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % F
% Gly: 0 0 8 0 0 8 0 8 31 39 31 0 0 24 16 % G
% His: 8 0 0 0 8 0 0 0 0 0 8 0 0 8 0 % H
% Ile: 0 8 0 0 0 0 0 0 8 0 0 16 0 0 0 % I
% Lys: 8 0 16 8 8 0 0 0 0 8 0 0 0 0 8 % K
% Leu: 8 31 0 0 8 0 0 0 0 16 8 39 0 0 24 % L
% Met: 0 8 0 0 0 8 0 0 0 16 0 0 0 0 0 % M
% Asn: 16 0 0 0 0 0 8 8 0 0 0 8 16 0 16 % N
% Pro: 16 16 0 8 0 8 24 16 8 0 8 0 0 0 8 % P
% Gln: 0 0 0 16 8 0 0 8 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 8 8 8 8 0 16 0 39 0 0 % R
% Ser: 16 8 16 24 31 31 0 16 8 8 0 0 0 31 16 % S
% Thr: 0 0 16 16 8 8 8 16 24 0 8 0 8 8 0 % T
% Val: 0 0 8 0 8 0 16 16 0 8 0 0 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _