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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPK3 All Species: 17.27
Human Site: S348 Identified Species: 31.67
UniProt: Q9UPE1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPE1 NP_055185 533 58997 S348 T G G L L S P S T P F G A S N
Chimpanzee Pan troglodytes XP_001160930 537 60598 L349 E G G H L C V L S P S T K T R
Rhesus Macaque Macaca mulatta XP_001088947 537 60682 V352 T K S L L P P V V F F R A A D
Dog Lupus familis XP_855347 537 59564 S352 T G G L L S P S T P F G A S N
Cat Felis silvestris
Mouse Mus musculus Q9Z0G2 565 62346 S380 T G G L L S P S T P F G A S N
Rat Rattus norvegicus NP_908934 563 62152 S378 T G G L L S P S T P F G A S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511138 531 59528 S337 G A Q V N G D S P H F T S H R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694973 707 78272 N523 E R S L L S P N S Y S A A D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649387 749 84628 I556 R Y R T E K K I T A K N Q S Q
Honey Bee Apis mellifera XP_001120563 589 66844 D380 T E S K G S P D I S E P S A P
Nematode Worm Caenorhab. elegans Q03563 1003 112508 S709 F G D L A S P S A E Y L S S P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002326404 560 63345 R319 K R G S R S N R Q N L L A S V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03656 742 83219 L500 T P L H E E Q L A D S L S T F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.1 68.3 87.9 N.A. 89.7 89.6 N.A. 69.2 N.A. N.A. 57.8 N.A. 36.9 52.4 30.3 N.A.
Protein Similarity: 100 81.5 80.2 89.9 N.A. 91.1 90.9 N.A. 78.6 N.A. N.A. 65.7 N.A. 48.3 65 38.9 N.A.
P-Site Identity: 100 26.6 40 100 N.A. 100 100 N.A. 13.3 N.A. N.A. 33.3 N.A. 13.3 20 40 N.A.
P-Site Similarity: 100 40 53.3 100 N.A. 100 100 N.A. 26.6 N.A. N.A. 46.6 N.A. 13.3 33.3 53.3 N.A.
Percent
Protein Identity: 42.3 N.A. N.A. N.A. 32.3 N.A.
Protein Similarity: 56.6 N.A. N.A. N.A. 47 N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 0 0 16 8 0 8 54 16 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 8 8 0 8 0 0 0 8 8 % D
% Glu: 16 8 0 0 16 8 0 0 0 8 8 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 47 0 0 0 16 % F
% Gly: 8 47 47 0 8 8 0 0 0 0 0 31 0 0 0 % G
% His: 0 0 0 16 0 0 0 0 0 8 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % I
% Lys: 8 8 0 8 0 8 8 0 0 0 8 0 8 0 0 % K
% Leu: 0 0 8 54 54 0 0 16 0 0 8 24 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 8 8 0 8 0 8 0 0 31 % N
% Pro: 0 8 0 0 0 8 62 0 8 39 0 8 0 0 16 % P
% Gln: 0 0 8 0 0 0 8 0 8 0 0 0 8 0 8 % Q
% Arg: 8 16 8 0 8 0 0 8 0 0 0 8 0 0 16 % R
% Ser: 0 0 24 8 0 62 0 47 16 8 24 0 31 54 0 % S
% Thr: 54 0 0 8 0 0 0 0 39 0 0 16 0 16 0 % T
% Val: 0 0 0 8 0 0 8 8 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _