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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK3
All Species:
33.03
Human Site:
S461
Identified Species:
60.56
UniProt:
Q9UPE1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPE1
NP_055185
533
58997
S461
I
P
P
A
F
A
L
S
G
R
Y
S
R
E
F
Chimpanzee
Pan troglodytes
XP_001160930
537
60598
S465
I
P
R
H
F
A
L
S
G
K
Y
S
R
E
F
Rhesus Macaque
Macaca mulatta
XP_001088947
537
60682
S465
I
P
R
H
F
A
L
S
G
K
Y
S
R
E
F
Dog
Lupus familis
XP_855347
537
59564
S465
I
P
P
A
F
A
L
S
G
R
Y
S
R
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0G2
565
62346
S493
I
P
P
A
F
A
L
S
G
R
Y
S
R
E
F
Rat
Rattus norvegicus
NP_908934
563
62152
S491
I
P
P
A
F
A
L
S
G
R
Y
S
R
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511138
531
59528
S459
I
P
P
H
F
A
L
S
G
R
Y
S
R
E
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694973
707
78272
S635
I
P
P
H
F
A
L
S
G
R
Y
S
R
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649387
749
84628
R673
I
P
Q
S
V
I
F
R
G
K
H
G
L
K
Y
Honey Bee
Apis mellifera
XP_001120563
589
66844
S515
I
P
R
H
I
A
L
S
G
K
N
S
K
M
Y
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
K834
I
P
P
S
I
Y
K
K
G
K
H
W
R
E
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326404
560
63345
G420
M
P
R
K
I
A
L
G
G
R
Y
S
R
D
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
N636
L
P
S
Y
L
L
R
N
G
K
Y
T
R
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.1
68.3
87.9
N.A.
89.7
89.6
N.A.
69.2
N.A.
N.A.
57.8
N.A.
36.9
52.4
30.3
N.A.
Protein Similarity:
100
81.5
80.2
89.9
N.A.
91.1
90.9
N.A.
78.6
N.A.
N.A.
65.7
N.A.
48.3
65
38.9
N.A.
P-Site Identity:
100
80
80
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
86.6
N.A.
20
46.6
46.6
N.A.
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
93.3
N.A.
53.3
66.6
66.6
N.A.
Percent
Protein Identity:
42.3
N.A.
N.A.
N.A.
32.3
N.A.
Protein Similarity:
56.6
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
60
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
31
0
77
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% E
% Phe:
0
0
0
0
62
0
8
0
0
0
0
0
0
0
70
% F
% Gly:
0
0
0
0
0
0
0
8
100
0
0
8
0
0
0
% G
% His:
0
0
0
39
0
0
0
0
0
0
16
0
0
0
0
% H
% Ile:
85
0
0
0
24
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
8
8
0
47
0
0
8
8
0
% K
% Leu:
8
0
0
0
8
8
77
0
0
0
0
0
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
100
54
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
31
0
0
0
8
8
0
54
0
0
85
0
0
% R
% Ser:
0
0
8
16
0
0
0
70
0
0
0
77
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
77
0
0
0
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _