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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK3
All Species:
43.94
Human Site:
S521
Identified Species:
80.56
UniProt:
Q9UPE1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPE1
NP_055185
533
58997
S521
Y
I
P
E
K
R
A
S
A
A
D
C
L
Q
H
Chimpanzee
Pan troglodytes
XP_001160930
537
60598
S525
M
V
P
E
K
R
A
S
A
G
E
C
L
R
H
Rhesus Macaque
Macaca mulatta
XP_001088947
537
60682
S525
M
V
P
E
K
R
A
S
A
G
E
C
L
R
H
Dog
Lupus familis
XP_855347
537
59564
S525
Y
I
P
E
K
R
A
S
A
A
D
C
L
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0G2
565
62346
S553
Y
I
P
E
K
R
A
S
A
A
D
C
L
Q
H
Rat
Rattus norvegicus
NP_908934
563
62152
S551
Y
I
P
E
K
R
A
S
A
A
D
C
L
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511138
531
59528
S519
Y
V
P
E
K
R
A
S
A
A
A
C
L
R
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694973
707
78272
T695
F
I
P
E
K
R
A
T
A
A
Q
C
L
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649387
749
84628
S733
Y
N
P
V
I
R
A
S
A
A
E
C
L
Q
H
Honey Bee
Apis mellifera
XP_001120563
589
66844
T575
F
D
P
S
T
R
A
T
A
A
E
C
L
K
H
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
T894
F
D
Q
E
K
R
S
T
A
K
I
A
L
K
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326404
560
63345
T480
F
V
P
E
K
R
P
T
A
A
Q
C
L
L
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
D696
L
D
P
R
K
R
A
D
A
G
G
L
V
N
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.1
68.3
87.9
N.A.
89.7
89.6
N.A.
69.2
N.A.
N.A.
57.8
N.A.
36.9
52.4
30.3
N.A.
Protein Similarity:
100
81.5
80.2
89.9
N.A.
91.1
90.9
N.A.
78.6
N.A.
N.A.
65.7
N.A.
48.3
65
38.9
N.A.
P-Site Identity:
100
66.6
66.6
100
N.A.
100
100
N.A.
80
N.A.
N.A.
80
N.A.
73.3
53.3
40
N.A.
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
93.3
N.A.
80
80
66.6
N.A.
Percent
Protein Identity:
42.3
N.A.
N.A.
N.A.
32.3
N.A.
Protein Similarity:
56.6
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
60
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
85
0
100
70
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
85
0
0
0
% C
% Asp:
0
24
0
0
0
0
0
8
0
0
31
0
0
0
0
% D
% Glu:
0
0
0
77
0
0
0
0
0
0
31
0
0
0
0
% E
% Phe:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
24
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
0
39
0
0
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
85
0
0
0
0
8
0
0
0
16
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
8
93
8
0
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
93
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
16
0
0
47
0
% Q
% Arg:
0
0
0
8
0
100
0
0
0
0
0
0
0
24
0
% R
% Ser:
0
0
0
8
0
0
8
62
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
31
0
0
0
0
0
0
0
% T
% Val:
0
31
0
8
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _