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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK3
All Species:
25.45
Human Site:
Y487
Identified Species:
46.67
UniProt:
Q9UPE1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPE1
NP_055185
533
58997
Y487
N
L
K
H
W
G
L
Y
E
V
L
M
E
K
Y
Chimpanzee
Pan troglodytes
XP_001160930
537
60598
F491
K
L
K
P
W
S
L
F
D
V
L
V
E
K
Y
Rhesus Macaque
Macaca mulatta
XP_001088947
537
60682
F491
K
L
K
P
W
S
L
F
D
V
L
V
E
K
Y
Dog
Lupus familis
XP_855347
537
59564
Y491
N
L
K
H
W
G
L
Y
E
V
L
M
E
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0G2
565
62346
Y519
N
L
K
H
W
G
L
Y
E
V
L
M
E
K
Y
Rat
Rattus norvegicus
NP_908934
563
62152
Y517
N
L
K
H
W
G
L
Y
E
V
L
M
E
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511138
531
59528
Y485
N
L
K
H
W
G
L
Y
E
V
L
L
E
K
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694973
707
78272
F661
N
L
K
P
W
G
L
F
E
V
L
L
E
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649387
749
84628
M699
K
L
K
P
W
S
L
M
N
V
L
V
E
K
Y
Honey Bee
Apis mellifera
XP_001120563
589
66844
Y541
G
L
K
P
W
G
L
Y
E
V
L
I
E
K
Y
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
Y860
Q
L
K
P
W
S
L
Y
E
V
L
R
Q
K
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326404
560
63345
N446
R
L
R
F
W
P
L
N
K
V
L
M
E
K
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
E662
K
L
K
F
W
P
L
E
D
V
L
T
E
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.1
68.3
87.9
N.A.
89.7
89.6
N.A.
69.2
N.A.
N.A.
57.8
N.A.
36.9
52.4
30.3
N.A.
Protein Similarity:
100
81.5
80.2
89.9
N.A.
91.1
90.9
N.A.
78.6
N.A.
N.A.
65.7
N.A.
48.3
65
38.9
N.A.
P-Site Identity:
100
60
60
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
80
N.A.
60
80
66.6
N.A.
P-Site Similarity:
100
80
80
100
N.A.
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
66.6
86.6
73.3
N.A.
Percent
Protein Identity:
42.3
N.A.
N.A.
N.A.
32.3
N.A.
Protein Similarity:
56.6
N.A.
N.A.
N.A.
47
N.A.
P-Site Identity:
60
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
62
0
0
0
93
0
0
% E
% Phe:
0
0
0
16
0
0
0
24
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
31
0
93
0
0
0
0
0
8
0
0
0
0
100
0
% K
% Leu:
0
100
0
0
0
0
100
0
0
0
100
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
39
0
0
0
% M
% Asn:
47
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
47
0
16
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
31
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
100
0
24
0
0
0
% V
% Trp:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
100
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _