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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLAGL2 All Species: 7.88
Human Site: S333 Identified Species: 21.67
UniProt: Q9UPG8 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPG8 NP_002648.1 496 54584 S333 P L E S S P I S S P A Q L P P
Chimpanzee Pan troglodytes XP_001172596 463 50830 S309 K Y N T T S T S Y S P L A S L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_542953 496 54620 S333 P L E S S P I S S P A Q L P P
Cat Felis silvestris
Mouse Mus musculus Q9QYE0 499 55564 S327 D M D A V H P S H H L A F K C
Rat Rattus norvegicus Q5U2T6 499 55622 S327 D M D T V H P S H H L A F K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514778 501 55494 P327 L D M D S V H P A H Q L S L K
Chicken Gallus gallus Q58NQ5 501 55939 P327 I D M E S V H P S H Q L S L K
Frog Xenopus laevis P18729 336 37535 K182 T C T E C G D K F A K K N N L
Zebra Danio Brachydanio rerio NP_705938 588 64361 M347 S L P T A M G M G C H M E P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 N.A. 98.9 N.A. 51.7 52.2 N.A. 52.8 52 24.3 54 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 54 N.A. 99.4 N.A. 66.5 67.1 N.A. 67.4 67.4 35.2 65.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 N.A. 100 N.A. 6.6 6.6 N.A. 6.6 13.3 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 N.A. 100 N.A. 26.6 26.6 N.A. 13.3 13.3 6.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 12 0 0 0 12 12 23 23 12 0 0 % A
% Cys: 0 12 0 0 12 0 0 0 0 12 0 0 0 0 23 % C
% Asp: 23 23 23 12 0 0 12 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 23 23 0 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 0 0 23 0 0 % F
% Gly: 0 0 0 0 0 12 12 0 12 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 23 23 0 23 45 12 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 0 0 0 0 0 12 0 0 12 12 0 23 23 % K
% Leu: 12 34 0 0 0 0 0 0 0 0 23 34 23 23 23 % L
% Met: 0 23 23 0 0 12 0 12 0 0 0 12 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 0 12 12 0 % N
% Pro: 23 0 12 0 0 23 23 23 0 23 12 0 0 34 34 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 23 23 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 0 23 45 12 0 56 34 12 0 0 23 12 0 % S
% Thr: 12 0 12 34 12 0 12 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 23 23 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _