KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX6
All Species:
18.18
Human Site:
Y139
Identified Species:
44.44
UniProt:
Q9UPM6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPM6
NP_055183.2
363
40045
Y139
A
R
C
G
R
Q
I
Y
A
S
D
W
V
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089041
363
40054
Y139
A
R
C
G
R
Q
I
Y
A
S
D
W
V
R
R
Dog
Lupus familis
XP_548475
390
43002
Y166
A
R
C
G
R
Q
I
Y
A
S
D
W
V
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1R0
363
40061
Y139
A
R
C
G
R
Q
I
Y
A
S
D
W
V
R
R
Rat
Rattus norvegicus
Q80W90
388
42915
R139
S
A
S
E
M
V
M
R
A
R
D
S
V
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512364
418
45485
Y194
A
R
C
G
R
Q
I
Y
A
S
D
W
V
R
R
Chicken
Gallus gallus
Q90881
397
44091
I140
C
A
R
C
H
L
G
I
S
A
S
E
M
V
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LWV4
396
44002
I140
C
A
R
C
H
L
G
I
S
A
S
E
M
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
F65
K
A
D
Y
S
K
N
F
G
A
K
C
S
K
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785118
357
38596
D135
A
R
C
L
R
N
I
D
A
S
D
W
V
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
91.5
N.A.
97.5
24.2
N.A.
81.3
23.4
N.A.
25
N.A.
34.4
N.A.
N.A.
39.3
Protein Similarity:
100
N.A.
100
92.5
N.A.
99.4
41.2
N.A.
84.6
41
N.A.
42.4
N.A.
47.3
N.A.
N.A.
51.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
20
N.A.
100
0
N.A.
0
N.A.
0
N.A.
N.A.
80
P-Site Similarity:
100
N.A.
100
100
N.A.
100
33.3
N.A.
100
20
N.A.
20
N.A.
26.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
40
0
0
0
0
0
0
70
30
0
0
0
0
0
% A
% Cys:
20
0
60
20
0
0
0
0
0
0
0
10
0
0
10
% C
% Asp:
0
0
10
0
0
0
0
10
0
0
70
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
50
0
0
20
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
60
20
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% K
% Leu:
0
0
0
10
0
20
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
20
0
20
% M
% Asn:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
60
20
0
60
0
0
10
0
10
0
0
0
60
60
% R
% Ser:
10
0
10
0
10
0
0
0
20
60
20
10
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
70
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
50
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _