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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4E1
All Species:
10
Human Site:
S667
Identified Species:
24.44
UniProt:
Q9UPM8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPM8
NP_031373.2
1137
127287
S667
E
P
Y
G
L
S
F
S
S
S
G
F
T
G
R
Chimpanzee
Pan troglodytes
XP_001169245
1137
127426
S667
E
P
Y
G
L
S
F
S
S
S
G
F
T
G
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535479
1138
127884
S668
P
Y
G
L
S
F
S
S
S
G
F
T
G
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80V94
1122
124787
S666
E
P
Y
G
L
S
F
S
S
S
G
F
T
G
R
Rat
Rattus norvegicus
P18484
938
104026
A485
A
A
K
T
V
F
E
A
L
Q
A
P
A
C
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699042
1121
123888
V658
P
Y
S
F
S
L
P
V
S
L
S
S
C
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
L487
A
K
T
V
F
E
A
L
Q
A
P
A
C
H
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328755
980
107167
C527
S
Y
V
T
G
K
L
C
D
V
A
E
S
Y
S
Maize
Zea mays
NP_001169710
969
105519
K516
E
Y
G
T
A
D
G
K
Y
S
A
S
Y
I
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12028
832
93606
F379
A
V
Q
R
H
R
K
F
I
S
H
C
L
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
91.7
N.A.
79.9
20.7
N.A.
N.A.
N.A.
N.A.
54.1
N.A.
21.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
95.5
N.A.
87.6
41.1
N.A.
N.A.
N.A.
N.A.
71.6
N.A.
42.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
13.3
N.A.
100
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
20
N.A.
100
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
31.4
30.4
N.A.
N.A.
20.9
N.A.
Protein Similarity:
49
48.7
N.A.
N.A.
38.6
N.A.
P-Site Identity:
0
13.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
6.6
13.3
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
10
0
0
10
0
10
10
0
10
30
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
10
20
10
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% D
% Glu:
40
0
0
0
0
10
10
0
0
0
0
10
0
0
10
% E
% Phe:
0
0
0
10
10
20
30
10
0
0
10
30
0
0
0
% F
% Gly:
0
0
20
30
10
0
10
0
0
10
30
0
10
30
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
10
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
20
% I
% Lys:
0
10
10
0
0
10
10
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
30
10
10
10
10
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
30
0
0
0
0
10
0
0
0
10
10
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
10
10
0
0
0
10
10
% Q
% Arg:
0
0
0
10
0
10
0
0
0
0
0
0
0
10
30
% R
% Ser:
10
0
10
0
20
30
10
40
50
50
10
20
10
10
10
% S
% Thr:
0
0
10
30
0
0
0
0
0
0
0
10
30
0
0
% T
% Val:
0
10
10
10
10
0
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
40
30
0
0
0
0
0
10
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _