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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP4E1 All Species: 9.39
Human Site: T1004 Identified Species: 22.96
UniProt: Q9UPM8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPM8 NP_031373.2 1137 127287 T1004 P F T E G N L T G F I S Y H M
Chimpanzee Pan troglodytes XP_001169245 1137 127426 T1004 P F T E G N L T G F I S Y H M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535479 1138 127884 T1005 P F T D G N L T G F I N Y Q M
Cat Felis silvestris
Mouse Mus musculus Q80V94 1122 124787 Q1003 M M D T H S V Q L E F S M N L
Rat Rattus norvegicus P18484 938 104026 L822 S V K L P I T L N K F F Q P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_699042 1121 123888 Q995 G S V S Y Q I Q P G H T N T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91926 940 105602 V824 S I K L P L S V N K F F E P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002328755 980 107167 V864 V T S S A P S V D P F R Q L E
Maize Zea mays NP_001169710 969 105519 E853 D L L D L G D E P V S S S P P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12028 832 93606 S716 S S A V E A N S G V T L P L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 91.7 N.A. 79.9 20.7 N.A. N.A. N.A. N.A. 54.1 N.A. 21.5 N.A. N.A. N.A.
Protein Similarity: 100 99.6 N.A. 95.5 N.A. 87.6 41.1 N.A. N.A. N.A. N.A. 71.6 N.A. 42.2 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 80 N.A. 6.6 0 N.A. N.A. N.A. N.A. 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 33.3 0 N.A. N.A. N.A. N.A. 20 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: 31.4 30.4 N.A. N.A. 20.9 N.A.
Protein Similarity: 49 48.7 N.A. N.A. 38.6 N.A.
P-Site Identity: 0 6.6 N.A. N.A. 6.6 N.A.
P-Site Similarity: 6.6 13.3 N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 20 0 0 10 0 10 0 0 0 0 0 10 % D
% Glu: 0 0 0 20 10 0 0 10 0 10 0 0 10 0 10 % E
% Phe: 0 30 0 0 0 0 0 0 0 30 40 20 0 0 0 % F
% Gly: 10 0 0 0 30 10 0 0 40 10 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 10 0 0 20 0 % H
% Ile: 0 10 0 0 0 10 10 0 0 0 30 0 0 0 0 % I
% Lys: 0 0 20 0 0 0 0 0 0 20 0 0 0 0 0 % K
% Leu: 0 10 10 20 10 10 30 10 10 0 0 10 0 20 20 % L
% Met: 10 10 0 0 0 0 0 0 0 0 0 0 10 0 30 % M
% Asn: 0 0 0 0 0 30 10 0 20 0 0 10 10 10 0 % N
% Pro: 30 0 0 0 20 10 0 0 20 10 0 0 10 30 10 % P
% Gln: 0 0 0 0 0 10 0 20 0 0 0 0 20 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 30 20 10 20 0 10 20 10 0 0 10 40 10 0 0 % S
% Thr: 0 10 30 10 0 0 10 30 0 0 10 10 0 10 20 % T
% Val: 10 10 10 10 0 0 10 20 0 20 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 30 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _