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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MACF1
All Species:
16.36
Human Site:
S1590
Identified Species:
45
UniProt:
Q9UPN3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPN3
NP_036222.3
5430
620418
S1590
S
A
L
Q
K
N
Q
S
D
L
K
D
L
Q
D
Chimpanzee
Pan troglodytes
XP_001170702
5430
620283
S1590
S
A
L
Q
K
N
Q
S
D
L
K
D
L
Q
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849152
5423
619404
S1590
S
T
L
Q
K
H
Q
S
D
L
K
D
L
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXZ0
5327
607958
V1591
L
L
C
A
E
P
K
V
D
L
K
D
L
Q
G
Rat
Rattus norvegicus
P30427
4687
533521
Q1387
N
S
Q
A
A
R
E
Q
L
R
Q
E
K
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515630
7036
790279
S3196
S
A
L
Q
Q
K
Q
S
D
L
E
D
L
Q
K
Chicken
Gallus gallus
XP_417817
5413
614999
S1588
P
A
L
Q
Q
R
Q
S
D
V
K
E
L
Q
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920094
5393
611479
R1584
H
T
L
Q
E
K
Q
R
A
L
K
D
V
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195605
3054
349588
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
95.3
N.A.
90
27.2
N.A.
64.9
82.2
N.A.
59.3
N.A.
N.A.
N.A.
N.A.
24.9
Protein Similarity:
100
99.8
N.A.
97.6
N.A.
93.5
46.7
N.A.
70.7
90.5
N.A.
76.3
N.A.
N.A.
N.A.
N.A.
38.8
P-Site Identity:
100
100
N.A.
86.6
N.A.
40
0
N.A.
73.3
60
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
53.3
33.3
N.A.
86.6
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
45
0
23
12
0
0
0
12
0
0
0
0
12
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
67
0
0
67
0
0
34
% D
% Glu:
0
0
0
0
23
0
12
0
0
0
12
23
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
34
23
12
0
0
0
67
0
12
0
23
% K
% Leu:
12
12
67
0
0
0
0
0
12
67
0
0
67
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
67
23
0
67
12
0
0
12
0
0
78
0
% Q
% Arg:
0
0
0
0
0
23
0
12
0
12
0
0
0
0
12
% R
% Ser:
45
12
0
0
0
0
0
56
0
0
0
0
0
0
0
% S
% Thr:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
12
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _