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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF8 All Species: 3.03
Human Site: S105 Identified Species: 6.06
UniProt: Q9UPP1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPP1 NP_055922.1 1060 117864 S105 M K K R R G S S K G H D T H K
Chimpanzee Pan troglodytes XP_521077 902 100718 L16 S S C K Q L P L P S F G D N H
Rhesus Macaque Macaca mulatta XP_001109325 941 106786 E54 D V N R F M I E C D I C K D W
Dog Lupus familis XP_549017 1024 113801 L104 D S S D E V I L K P T G S Q L
Cat Felis silvestris
Mouse Mus musculus Q80TJ7 1023 113535 L104 D S S D E V I L K P T G S Q L
Rat Rattus norvegicus NP_001101723 1023 113534 L104 D S S D E V I L K P T G S Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508529 1024 113352 Q114 I L K P T G T Q L T V E Y L E
Chicken Gallus gallus XP_414324 1061 118324 S111 I V V K V P G S Q L T T E Y L
Frog Xenopus laevis NP_001085579 419 48261
Zebra Danio Brachydanio rerio XP_694899 1032 114204 S102 L R C R T F P S A D E V L L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394272 917 104227 H31 D V C K E W Y H G G C V S I K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789776 951 107984 K65 G P T K L K K K K N W H R Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.3 39.1 93.7 N.A. 91.5 91.7 N.A. 76.3 50.5 26.4 61.5 N.A. N.A. 35.6 N.A. 36.5
Protein Similarity: 100 80.5 55.4 95.2 N.A. 94.2 94.3 N.A. 83.5 67.1 33.2 72 N.A. N.A. 51.7 N.A. 54.3
P-Site Identity: 100 0 6.6 6.6 N.A. 6.6 6.6 N.A. 13.3 6.6 0 20 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 20 6.6 13.3 N.A. 13.3 13.3 N.A. 40 33.3 0 33.3 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 25 0 0 0 0 0 9 0 9 9 0 0 0 % C
% Asp: 42 0 0 25 0 0 0 0 0 17 0 9 9 9 9 % D
% Glu: 0 0 0 0 34 0 0 9 0 0 9 9 9 0 9 % E
% Phe: 0 0 0 0 9 9 0 0 0 0 9 0 0 0 0 % F
% Gly: 9 0 0 0 0 17 9 0 9 17 0 34 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 9 9 0 9 9 % H
% Ile: 17 0 0 0 0 0 34 0 0 0 9 0 0 9 0 % I
% Lys: 0 9 17 34 0 9 9 9 42 0 0 0 9 0 25 % K
% Leu: 9 9 0 0 9 9 0 34 9 9 0 0 9 17 34 % L
% Met: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 9 0 0 0 9 0 % N
% Pro: 0 9 0 9 0 9 17 0 9 25 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 9 9 0 0 0 0 34 0 % Q
% Arg: 0 9 0 25 9 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 9 34 25 0 0 0 9 25 0 9 0 0 34 0 0 % S
% Thr: 0 0 9 0 17 0 9 0 0 9 34 9 9 0 0 % T
% Val: 0 25 9 0 9 25 0 0 0 0 9 17 0 0 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _