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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF8 All Species: 0.3
Human Site: S129 Identified Species: 0.61
UniProt: Q9UPP1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPP1 NP_055922.1 1060 117864 S129 T F V R E L R S R T F D S S D
Chimpanzee Pan troglodytes XP_521077 902 100718 K40 N N A E T V G K S P A Y R R C
Rhesus Macaque Macaca mulatta XP_001109325 941 106786 D78 E H H A V D I D L Y H C P N C
Dog Lupus familis XP_549017 1024 113801 L128 F S V P I L V L K K D G L G M
Cat Felis silvestris
Mouse Mus musculus Q80TJ7 1023 113535 L128 F S V P I L V L K K D G L G M
Rat Rattus norvegicus NP_001101723 1023 113534 L128 F S V P I L V L K K D G L G M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508529 1024 113352 G138 V L K K D G L G M T L P S P T
Chicken Gallus gallus XP_414324 1061 118324 L135 L V P K K D G L G L S V P A P
Frog Xenopus laevis NP_001085579 419 48261
Zebra Danio Brachydanio rerio XP_694899 1032 114204 S126 F L E E R S F S V P V L V L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394272 917 104227 A55 Y H C P R C E A M C G P S I M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789776 951 107984 R89 I G T A V F L R Q L K N R A F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.3 39.1 93.7 N.A. 91.5 91.7 N.A. 76.3 50.5 26.4 61.5 N.A. N.A. 35.6 N.A. 36.5
Protein Similarity: 100 80.5 55.4 95.2 N.A. 94.2 94.3 N.A. 83.5 67.1 33.2 72 N.A. N.A. 51.7 N.A. 54.3
P-Site Identity: 100 0 0 13.3 N.A. 13.3 13.3 N.A. 13.3 0 0 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 6.6 6.6 20 N.A. 20 20 N.A. 26.6 20 0 6.6 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 17 0 0 0 9 0 0 9 0 0 17 0 % A
% Cys: 0 0 9 0 0 9 0 0 0 9 0 9 0 0 17 % C
% Asp: 0 0 0 0 9 17 0 9 0 0 25 9 0 0 9 % D
% Glu: 9 0 9 17 9 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 34 9 0 0 0 9 9 0 0 0 9 0 0 0 9 % F
% Gly: 0 9 0 0 0 9 17 9 9 0 9 25 0 25 0 % G
% His: 0 17 9 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 9 0 0 0 25 0 9 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 9 17 9 0 0 9 25 25 9 0 0 0 0 % K
% Leu: 9 17 0 0 0 34 17 34 9 17 9 9 25 9 0 % L
% Met: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 34 % M
% Asn: 9 9 0 0 0 0 0 0 0 0 0 9 0 9 0 % N
% Pro: 0 0 9 34 0 0 0 0 0 17 0 17 17 9 9 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 17 0 9 9 9 0 0 0 17 9 9 % R
% Ser: 0 25 0 0 0 9 0 17 9 0 9 0 25 9 0 % S
% Thr: 9 0 9 0 9 0 0 0 0 17 0 0 0 0 9 % T
% Val: 9 9 34 0 17 9 25 0 9 0 9 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _