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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF8 All Species: 4.24
Human Site: S613 Identified Species: 8.48
UniProt: Q9UPP1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPP1 NP_055922.1 1060 117864 S613 A L L M S N G S T K R V K S L
Chimpanzee Pan troglodytes XP_521077 902 100718 A496 R A W T R K E A L P D H E D E
Rhesus Macaque Macaca mulatta XP_001109325 941 106786 E534 I L E L H T R E V L K R L E M
Dog Lupus familis XP_549017 1024 113801 K586 K R V K S L S K S R R A K L T
Cat Felis silvestris
Mouse Mus musculus Q80TJ7 1023 113535 S585 T K R M K S V S K S R R A K I
Rat Rattus norvegicus NP_001101723 1023 113534 S587 R M K S V S K S R R A K I A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508529 1024 113352 R594 K K V K A S T R S R S S K A T
Chicken Gallus gallus XP_414324 1061 118324 T600 R E Q N K S K T E A K W K Y K
Frog Xenopus laevis NP_001085579 419 48261 Q13 P V Y C V C R Q P Y D V S R F
Zebra Danio Brachydanio rerio XP_694899 1032 114204 R582 K L Q G K K G R A G S A N G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394272 917 104227 G511 I S E P P S S G R P P L K L T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789776 951 107984 R545 D E R H R K K R K K N T T K N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.3 39.1 93.7 N.A. 91.5 91.7 N.A. 76.3 50.5 26.4 61.5 N.A. N.A. 35.6 N.A. 36.5
Protein Similarity: 100 80.5 55.4 95.2 N.A. 94.2 94.3 N.A. 83.5 67.1 33.2 72 N.A. N.A. 51.7 N.A. 54.3
P-Site Identity: 100 0 6.6 20 N.A. 20 6.6 N.A. 6.6 6.6 6.6 13.3 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 13.3 26.6 40 N.A. 33.3 33.3 N.A. 46.6 26.6 13.3 13.3 N.A. N.A. 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 0 0 9 9 9 9 17 9 17 9 % A
% Cys: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 17 0 0 9 0 % D
% Glu: 0 17 17 0 0 0 9 9 9 0 0 0 9 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 9 0 0 17 9 0 9 0 0 0 9 0 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 17 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % I
% Lys: 25 17 9 17 25 25 25 9 17 17 17 9 42 17 17 % K
% Leu: 0 25 9 9 0 9 0 0 9 9 0 9 9 17 9 % L
% Met: 0 9 0 17 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 9 0 9 0 0 0 0 9 0 9 0 9 % N
% Pro: 9 0 0 9 9 0 0 0 9 17 9 0 0 0 0 % P
% Gln: 0 0 17 0 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 25 9 17 0 17 0 17 25 17 25 25 17 0 9 0 % R
% Ser: 0 9 0 9 17 42 17 25 17 9 17 9 9 9 0 % S
% Thr: 9 0 0 9 0 9 9 9 9 0 0 9 9 0 25 % T
% Val: 0 9 17 0 17 0 9 0 9 0 0 17 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _