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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF8 All Species: 8.18
Human Site: S866 Identified Species: 16.36
UniProt: Q9UPP1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPP1 NP_055922.1 1060 117864 S866 D D D P A L K S R P K K K K N
Chimpanzee Pan troglodytes XP_521077 902 100718 K730 P R K L P R A K P C S D P N R
Rhesus Macaque Macaca mulatta XP_001109325 941 106786 P769 E R N S L Q D P S S C H S S N
Dog Lupus familis XP_549017 1024 113801 S830 D D D P A L K S R P K K K K N
Cat Felis silvestris
Mouse Mus musculus Q80TJ7 1023 113535 R830 D D P A L K S R P K K K K N S
Rat Rattus norvegicus NP_001101723 1023 113534 R830 D D P A L K S R P K K K K N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508529 1024 113352 C839 E D D P A L K C R P K K K K N
Chicken Gallus gallus XP_414324 1061 118324 V877 C F K D S D Y V Y P S L E S D
Frog Xenopus laevis NP_001085579 419 48261 Y247 L M G V K D S Y T D F H I D F
Zebra Danio Brachydanio rerio XP_694899 1032 114204 S823 E E D H V S K S K M K R K R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394272 917 104227 D745 T K M Q P D E D D D Q S I E N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789776 951 107984 Y779 F Q D A K Y V Y P S L D D D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.3 39.1 93.7 N.A. 91.5 91.7 N.A. 76.3 50.5 26.4 61.5 N.A. N.A. 35.6 N.A. 36.5
Protein Similarity: 100 80.5 55.4 95.2 N.A. 94.2 94.3 N.A. 83.5 67.1 33.2 72 N.A. N.A. 51.7 N.A. 54.3
P-Site Identity: 100 0 6.6 100 N.A. 33.3 33.3 N.A. 86.6 6.6 0 40 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 0 20 100 N.A. 40 40 N.A. 93.3 26.6 0 73.3 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 25 25 0 9 0 0 0 0 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 9 0 9 9 0 0 0 0 % C
% Asp: 34 42 42 9 0 25 9 9 9 17 0 17 9 17 9 % D
% Glu: 25 9 0 0 0 0 9 0 0 0 0 0 9 9 0 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 9 0 0 0 9 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 17 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % I
% Lys: 0 9 17 0 17 17 34 9 9 17 50 42 50 25 0 % K
% Leu: 9 0 0 9 25 25 0 0 0 0 9 9 0 0 0 % L
% Met: 0 9 9 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 25 50 % N
% Pro: 9 0 17 25 17 0 0 9 34 34 0 0 9 0 0 % P
% Gln: 0 9 0 9 0 9 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 17 0 0 0 9 0 17 25 0 0 9 0 9 9 % R
% Ser: 0 0 0 9 9 9 25 25 9 17 17 9 9 17 17 % S
% Thr: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % T
% Val: 0 0 0 9 9 0 9 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 9 17 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _