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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF8 All Species: 15.76
Human Site: S904 Identified Species: 31.52
UniProt: Q9UPP1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPP1 NP_055922.1 1060 117864 S904 R E G T R V A S I E T G L A A
Chimpanzee Pan troglodytes XP_521077 902 100718 N768 G V E G K L G N G S G A G G I
Rhesus Macaque Macaca mulatta XP_001109325 941 106786 W807 P D L R T S S W I K Q F D T S
Dog Lupus familis XP_549017 1024 113801 S868 R E G T R V A S I E T G L A A
Cat Felis silvestris
Mouse Mus musculus Q80TJ7 1023 113535 I868 E G T R V A S I E T G L A A A
Rat Rattus norvegicus NP_001101723 1023 113534 I868 E G T R V A S I E T G L A A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508529 1024 113352 S877 R E G T R V A S I E T G L A A
Chicken Gallus gallus XP_414324 1061 118324 V915 T A R V G P S V P R Q D R P V
Frog Xenopus laevis NP_001085579 419 48261 S285 E N L A L Y E S W S S S V T Q
Zebra Danio Brachydanio rerio XP_694899 1032 114204 S861 R E G A R V A S V E T G L A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394272 917 104227 S783 I F K P K A K S Q I D E A W N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789776 951 107984 S817 K A K V L T P S Q K L I R P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.3 39.1 93.7 N.A. 91.5 91.7 N.A. 76.3 50.5 26.4 61.5 N.A. N.A. 35.6 N.A. 36.5
Protein Similarity: 100 80.5 55.4 95.2 N.A. 94.2 94.3 N.A. 83.5 67.1 33.2 72 N.A. N.A. 51.7 N.A. 54.3
P-Site Identity: 100 0 6.6 100 N.A. 13.3 13.3 N.A. 100 0 6.6 86.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 20 33.3 100 N.A. 20 20 N.A. 100 6.6 20 93.3 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 17 0 25 34 0 0 0 0 9 25 50 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 9 9 9 0 0 % D
% Glu: 25 34 9 0 0 0 9 0 17 34 0 9 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 9 17 34 9 9 0 9 0 9 0 25 34 9 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 17 34 9 0 9 0 0 9 % I
% Lys: 9 0 17 0 17 0 9 0 0 17 0 0 0 0 0 % K
% Leu: 0 0 17 0 17 9 0 0 0 0 9 17 34 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % N
% Pro: 9 0 0 9 0 9 9 0 9 0 0 0 0 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 17 0 17 0 0 0 9 % Q
% Arg: 34 0 9 25 34 0 0 0 0 9 0 0 17 0 0 % R
% Ser: 0 0 0 0 0 9 34 59 0 17 9 9 0 0 9 % S
% Thr: 9 0 17 25 9 9 0 0 0 17 34 0 0 17 0 % T
% Val: 0 9 0 17 17 34 0 9 9 0 0 0 9 0 17 % V
% Trp: 0 0 0 0 0 0 0 9 9 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _