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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF8 All Species: 14.85
Human Site: Y929 Identified Species: 29.7
UniProt: Q9UPP1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPP1 NP_055922.1 1060 117864 Y929 Q K A Q K K K Y I K K K P L L
Chimpanzee Pan troglodytes XP_521077 902 100718 G786 L K A S R Q V G G P D Y A A L
Rhesus Macaque Macaca mulatta XP_001109325 941 106786 Q825 P Q D L S R S Q K C I K K E G
Dog Lupus familis XP_549017 1024 113801 Y893 Q K A Q K K K Y I K K K P L L
Cat Felis silvestris
Mouse Mus musculus Q80TJ7 1023 113535 Y892 Q K A Q K K K Y I K K K P L L
Rat Rattus norvegicus NP_001101723 1023 113534 Y892 Q K A Q K K K Y I K K K P L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508529 1024 113352 K896 L A Q Q E H Q K I Q K R K Y F
Chicken Gallus gallus XP_414324 1061 118324 T933 T R V A S I E T G L A A A A A
Frog Xenopus laevis NP_001085579 419 48261 K303 F F G D K V D K C Y K C V V K
Zebra Danio Brachydanio rerio XP_694899 1032 114204 I882 Q Q E Q Q K T I T K R K Y T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394272 917 104227 K801 R V G P L L P K T N R P A R E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789776 951 107984 T835 A R R P N I E T G L A D A A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.3 39.1 93.7 N.A. 91.5 91.7 N.A. 76.3 50.5 26.4 61.5 N.A. N.A. 35.6 N.A. 36.5
Protein Similarity: 100 80.5 55.4 95.2 N.A. 94.2 94.3 N.A. 83.5 67.1 33.2 72 N.A. N.A. 51.7 N.A. 54.3
P-Site Identity: 100 20 6.6 100 N.A. 100 100 N.A. 20 0 13.3 33.3 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 33.3 20 100 N.A. 100 100 N.A. 46.6 13.3 20 53.3 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 42 9 0 0 0 0 0 0 17 9 34 25 17 % A
% Cys: 0 0 0 0 0 0 0 0 9 9 0 9 0 0 0 % C
% Asp: 0 0 9 9 0 0 9 0 0 0 9 9 0 0 0 % D
% Glu: 0 0 9 0 9 0 17 0 0 0 0 0 0 9 9 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 17 0 0 0 0 9 25 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 17 0 9 42 0 9 0 0 0 0 % I
% Lys: 0 42 0 0 42 42 34 25 9 42 50 50 17 0 17 % K
% Leu: 17 0 0 9 9 9 0 0 0 17 0 0 0 34 42 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 9 0 0 17 0 0 9 0 0 9 0 9 34 0 0 % P
% Gln: 42 17 9 50 9 9 9 9 0 9 0 0 0 0 0 % Q
% Arg: 9 17 9 0 9 9 0 0 0 0 17 9 0 9 0 % R
% Ser: 0 0 0 9 17 0 9 0 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 9 17 17 0 0 0 0 9 0 % T
% Val: 0 9 9 0 0 9 9 0 0 0 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 34 0 9 0 9 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _