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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQSEC3
All Species:
7.27
Human Site:
S553
Identified Species:
22.86
UniProt:
Q9UPP2
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPP2
NP_056047.1
1182
127621
S553
E
D
A
S
A
E
D
S
C
A
E
A
A
A
S
Chimpanzee
Pan troglodytes
XP_516294
1034
115556
K490
G
G
Q
Q
G
S
P
K
H
G
P
H
S
G
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543874
1203
129435
T563
G
A
A
H
A
E
N
T
C
A
E
A
G
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TES0
1195
129101
Q556
E
A
A
E
S
R
A
Q
S
A
Q
E
P
A
V
Rat
Rattus norvegicus
Q76M68
1194
129000
Q554
E
A
A
E
S
G
A
Q
S
A
H
E
P
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416377
951
105942
S407
Y
H
C
E
N
P
A
S
C
K
S
P
T
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001335484
858
95491
S314
S
T
S
T
S
A
Q
S
A
S
E
V
S
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396854
1053
118476
S509
K
H
K
G
I
S
S
S
P
E
H
Q
E
C
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.5
N.A.
88.1
N.A.
85.9
85.3
N.A.
N.A.
59.6
N.A.
43.7
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
100
46.6
N.A.
90.6
N.A.
89.1
88.8
N.A.
N.A.
66.5
N.A.
53.4
N.A.
N.A.
46.5
N.A.
N.A.
P-Site Identity:
100
0
N.A.
53.3
N.A.
26.6
20
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
13.3
N.A.
66.6
N.A.
40
26.6
N.A.
N.A.
20
N.A.
53.3
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
38
50
0
25
13
38
0
13
50
0
25
13
38
13
% A
% Cys:
0
0
13
0
0
0
0
0
38
0
0
0
0
13
0
% C
% Asp:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
38
0
0
38
0
25
0
0
0
13
38
25
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
25
13
0
13
13
13
0
0
0
13
0
0
13
13
0
% G
% His:
0
25
0
13
0
0
0
0
13
0
25
13
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
13
0
0
0
0
13
0
13
0
0
0
0
13
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
13
13
0
13
0
13
13
25
0
0
% P
% Gln:
0
0
13
13
0
0
13
25
0
0
13
13
0
0
0
% Q
% Arg:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
13
% R
% Ser:
13
0
13
13
38
25
13
50
25
13
13
0
25
13
25
% S
% Thr:
0
13
0
13
0
0
0
13
0
0
0
0
13
13
13
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _