KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZRN3
All Species:
24.24
Human Site:
S375
Identified Species:
59.26
UniProt:
Q9UPQ7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPQ7
NP_055824.1
1066
119596
S375
M
A
L
T
K
M
S
S
P
S
P
P
V
L
D
Chimpanzee
Pan troglodytes
XP_516586
1066
119550
S375
M
A
L
T
K
M
S
S
P
S
P
P
V
L
D
Rhesus Macaque
Macaca mulatta
XP_001098466
1332
148251
S634
M
A
L
T
K
M
S
S
P
S
P
P
V
L
D
Dog
Lupus familis
XP_543731
899
101581
Y262
D
R
A
E
D
F
E
Y
E
E
V
E
L
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZS0
1063
119397
S375
M
A
L
T
K
M
S
S
P
S
P
P
V
L
D
Rat
Rattus norvegicus
P68907
1062
119270
S374
M
A
L
T
K
I
S
S
P
S
P
P
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505476
763
86972
G158
T
D
D
E
E
D
T
G
I
Y
V
S
E
V
D
Chicken
Gallus gallus
XP_414432
1060
119396
P373
A
L
S
K
M
G
S
P
T
P
P
V
S
V
L
Frog
Xenopus laevis
NP_001090510
1029
116923
S343
A
A
L
A
K
I
S
S
P
S
P
S
V
A
R
Zebra Danio
Brachydanio rerio
XP_001344551
1053
118438
T374
M
A
L
S
K
L
P
T
S
S
T
P
V
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
79.2
53.8
N.A.
94.4
94
N.A.
44.5
83
73.5
72.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
79.7
66.4
N.A.
96.9
96.4
N.A.
57.1
90.3
83.2
83.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
86.6
N.A.
6.6
13.3
60
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
93.3
N.A.
26.6
20
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
70
10
10
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
10
10
0
10
10
0
0
0
0
0
0
0
10
50
% D
% Glu:
0
0
0
20
10
0
10
0
10
10
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
70
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
70
0
0
10
0
0
0
0
0
0
10
50
10
% L
% Met:
60
0
0
0
10
40
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
60
10
70
60
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
20
% R
% Ser:
0
0
10
10
0
0
70
60
10
70
0
20
10
0
0
% S
% Thr:
10
0
0
50
0
0
10
10
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
20
10
70
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _