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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOLK
All Species:
16.06
Human Site:
S323
Identified Species:
39.26
UniProt:
Q9UPQ8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPQ8
NP_055723.1
538
59268
S323
L
Y
Q
N
A
K
R
S
S
S
E
S
K
K
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537820
536
59260
S321
L
Y
Q
N
A
K
R
S
S
S
E
S
K
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2Y3
534
59127
S319
L
Y
Q
N
A
K
R
S
S
S
E
S
K
K
H
Rat
Rattus norvegicus
NP_001101296
536
59200
S321
L
Y
Q
N
A
K
R
S
S
S
E
S
K
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517971
485
52832
S271
G
L
V
W
L
Q
N
S
K
R
S
S
A
E
S
Chicken
Gallus gallus
XP_415482
523
58204
R308
V
F
Y
Q
N
A
K
R
S
S
E
S
K
K
H
Frog
Xenopus laevis
NP_001086008
521
57639
S306
V
V
V
L
Y
Q
N
S
K
R
S
P
D
S
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313531
573
64284
S355
W
V
C
V
I
Y
L
S
V
L
R
F
Y
N
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190090
569
63118
I351
C
I
Y
W
I
L
L
I
V
V
S
V
S
R
F
Baker's Yeast
Sacchar. cerevisiae
P20048
519
58888
K300
L
E
S
T
I
R
Q
K
I
L
F
A
W
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.2
N.A.
94.8
94.9
N.A.
69.6
76.2
69.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
96.4
N.A.
96.4
96.4
N.A.
79.3
87.1
83.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
46.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
26.6
66.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
24.6
N.A.
N.A.
26.8
23.4
N.A.
Protein Similarity:
45.2
N.A.
N.A.
46
44.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
40
10
0
0
0
0
0
10
10
0
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
50
0
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
10
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% H
% Ile:
0
10
0
0
30
0
0
10
10
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
40
10
10
20
0
0
0
50
50
10
% K
% Leu:
50
10
0
10
10
10
20
0
0
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
40
10
0
20
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
40
10
0
20
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
40
10
0
20
10
0
0
10
0
% R
% Ser:
0
0
10
0
0
0
0
70
50
50
30
60
10
20
20
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
20
20
20
10
0
0
0
0
20
10
0
10
0
0
0
% V
% Trp:
10
0
0
20
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
40
20
0
10
10
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _