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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOLK
All Species:
20.3
Human Site:
Y501
Identified Species:
49.63
UniProt:
Q9UPQ8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPQ8
NP_055723.1
538
59268
Y501
D
S
G
V
D
L
N
Y
S
Y
A
W
I
L
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537820
536
59260
Y499
D
S
G
V
D
L
N
Y
S
Y
V
W
I
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2Y3
534
59127
Y497
D
S
G
V
D
L
N
Y
S
Y
A
W
I
L
G
Rat
Rattus norvegicus
NP_001101296
536
59200
Y499
D
S
G
V
D
L
N
Y
S
Y
A
W
I
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517971
485
52832
G449
S
G
V
E
L
D
S
G
Y
A
W
I
L
G
S
Chicken
Gallus gallus
XP_415482
523
58204
S486
D
S
S
V
N
L
N
S
S
Y
A
W
I
L
V
Frog
Xenopus laevis
NP_001086008
521
57639
S484
D
S
S
V
N
L
N
S
G
Y
V
W
I
L
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313531
573
64284
F533
H
L
A
S
T
G
Y
F
L
T
E
H
W
I
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190090
569
63118
I529
I
L
A
S
M
G
Y
I
L
S
Q
G
W
W
S
Baker's Yeast
Sacchar. cerevisiae
P20048
519
58888
H478
D
K
A
A
I
F
N
H
L
T
T
L
Q
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.2
N.A.
94.8
94.9
N.A.
69.6
76.2
69.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
96.4
N.A.
96.4
96.4
N.A.
79.3
87.1
83.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
0
73.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
13.3
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
24.6
N.A.
N.A.
26.8
23.4
N.A.
Protein Similarity:
45.2
N.A.
N.A.
46
44.8
N.A.
P-Site Identity:
0
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
10
0
0
0
0
0
10
40
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
0
0
0
40
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
40
0
0
20
0
10
10
0
0
10
0
10
50
% G
% His:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
10
0
0
10
0
0
0
10
60
10
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
0
0
10
60
0
0
30
0
0
10
10
70
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
70
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
60
20
20
0
0
10
20
50
10
0
0
0
0
30
% S
% Thr:
0
0
0
0
10
0
0
0
0
20
10
0
0
0
0
% T
% Val:
0
0
10
60
0
0
0
0
0
0
20
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
60
20
10
0
% W
% Tyr:
0
0
0
0
0
0
20
40
10
60
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _