KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
21.52
Human Site:
S1113
Identified Species:
36.41
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
S1113
D
V
Q
K
P
R
R
S
L
E
V
I
P
E
K
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
S1302
D
V
Q
K
P
R
R
S
L
E
V
I
P
E
K
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
S1020
D
V
Q
K
P
R
R
S
L
E
V
I
P
E
K
Dog
Lupus familis
XP_542772
1140
126851
S1126
D
V
Q
K
P
R
R
S
L
E
V
I
P
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
S1114
E
A
Q
K
P
R
R
S
L
E
A
I
P
E
K
Rat
Rattus norvegicus
Q62688
1096
122754
L1081
E
A
K
G
K
R
S
L
E
A
I
E
E
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
S1037
E
V
S
K
P
R
R
S
L
E
A
I
P
E
K
Chicken
Gallus gallus
Q2VRL0
637
72514
K624
L
F
S
K
S
G
G
K
L
E
P
A
S
L
F
Frog
Xenopus laevis
Q32NH8
758
87399
H745
P
P
A
S
L
F
V
H
I
R
V
T
D
A
S
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
G771
H
V
K
V
V
R
R
G
V
H
I
K
T
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
D1076
T
D
V
Q
K
L
M
D
M
Y
K
I
E
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
R1054
I
I
R
K
N
G
R
R
F
S
R
V
I
A
D
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
A639
T
A
T
S
L
K
Q
A
H
E
G
D
I
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
Q856
L
F
N
M
E
G
E
Q
Y
I
F
C
T
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
100
100
N.A.
80
6.6
N.A.
80
20
6.6
20
N.A.
13.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
40
N.A.
86.6
20
13.3
40
N.A.
33.3
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
8
0
0
0
0
8
0
8
15
8
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
29
8
0
0
0
0
0
8
0
0
0
8
8
0
8
% D
% Glu:
22
0
0
0
8
0
8
0
8
58
0
8
15
50
22
% E
% Phe:
0
15
0
0
0
8
0
0
8
0
8
0
0
0
15
% F
% Gly:
0
0
0
8
0
22
8
8
0
0
8
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
8
8
15
50
15
0
0
% I
% Lys:
0
0
15
58
15
8
0
8
0
0
8
8
0
8
43
% K
% Leu:
15
0
0
0
15
8
0
8
50
0
0
0
0
15
0
% L
% Met:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
43
0
0
0
0
0
8
0
43
0
0
% P
% Gln:
0
0
36
8
0
0
8
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
0
58
58
8
0
8
8
0
0
0
0
% R
% Ser:
0
0
15
15
8
0
8
43
0
8
0
0
8
0
15
% S
% Thr:
15
0
8
0
0
0
0
0
0
0
0
8
15
0
0
% T
% Val:
0
43
8
8
8
0
8
0
8
0
36
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _