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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCL2 All Species: 21.52
Human Site: S1113 Identified Species: 36.41
UniProt: Q9UPR0 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPR0 NP_001137854.1 1127 125866 S1113 D V Q K P R R S L E V I P E K
Chimpanzee Pan troglodytes XP_526146 1316 145538 S1302 D V Q K P R R S L E V I P E K
Rhesus Macaque Macaca mulatta XP_001084228 1034 116313 S1020 D V Q K P R R S L E V I P E K
Dog Lupus familis XP_542772 1140 126851 S1126 D V Q K P R R S L E V I P E K
Cat Felis silvestris
Mouse Mus musculus Q8K394 1128 125754 S1114 E A Q K P R R S L E A I P E K
Rat Rattus norvegicus Q62688 1096 122754 L1081 E A K G K R S L E A I E E K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507313 1051 118878 S1037 E V S K P R R S L E A I P E K
Chicken Gallus gallus Q2VRL0 637 72514 K624 L F S K S G G K L E P A S L F
Frog Xenopus laevis Q32NH8 758 87399 H745 P P A S L F V H I R V T D A S
Zebra Danio Brachydanio rerio A5D6R3 784 89362 G771 H V K V V R R G V H I K T V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 D1076 T D V Q K L M D M Y K I E E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_741067 1068 120024 R1054 I I R K N G R R F S R V I A D
Sea Urchin Strong. purpuratus XP_797105 652 73813 A639 T A T S L K Q A H E G D I Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 Q856 L F N M E G E Q Y I F C T L F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.6 86.5 97 N.A. 96.7 62.5 N.A. 85.5 23.2 27.8 27 N.A. 20.5 N.A. 38.3 34.4
Protein Similarity: 100 85.6 87.2 97.8 N.A. 98.2 76.4 N.A. 89.1 35.8 41.9 42.4 N.A. 40 N.A. 58 45.3
P-Site Identity: 100 100 100 100 N.A. 80 6.6 N.A. 80 20 6.6 20 N.A. 13.3 N.A. 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 40 N.A. 86.6 20 13.3 40 N.A. 33.3 N.A. 33.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 8 0 0 0 0 8 0 8 15 8 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 29 8 0 0 0 0 0 8 0 0 0 8 8 0 8 % D
% Glu: 22 0 0 0 8 0 8 0 8 58 0 8 15 50 22 % E
% Phe: 0 15 0 0 0 8 0 0 8 0 8 0 0 0 15 % F
% Gly: 0 0 0 8 0 22 8 8 0 0 8 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 8 8 8 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 8 8 15 50 15 0 0 % I
% Lys: 0 0 15 58 15 8 0 8 0 0 8 8 0 8 43 % K
% Leu: 15 0 0 0 15 8 0 8 50 0 0 0 0 15 0 % L
% Met: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 0 43 0 0 0 0 0 8 0 43 0 0 % P
% Gln: 0 0 36 8 0 0 8 8 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 0 58 58 8 0 8 8 0 0 0 0 % R
% Ser: 0 0 15 15 8 0 8 43 0 8 0 0 8 0 15 % S
% Thr: 15 0 8 0 0 0 0 0 0 0 0 8 15 0 0 % T
% Val: 0 43 8 8 8 0 8 0 8 0 36 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _