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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
14.24
Human Site:
S135
Identified Species:
24.1
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
S135
P
T
E
K
K
I
S
S
A
S
D
C
I
N
S
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
S324
P
T
E
K
K
I
S
S
A
S
D
C
I
N
S
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
S95
K
K
T
V
S
F
S
S
M
P
T
E
K
K
I
Dog
Lupus familis
XP_542772
1140
126851
S139
P
T
E
K
K
I
S
S
A
S
D
C
I
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
S136
P
T
E
K
K
I
S
S
A
S
D
C
I
N
S
Rat
Rattus norvegicus
Q62688
1096
122754
H110
E
K
K
I
S
S
A
H
D
C
I
S
F
M
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
I110
K
D
S
E
K
A
K
I
D
I
K
S
I
K
E
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
A128
I
C
P
D
A
A
T
A
K
S
W
Q
K
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
N110
Y
I
R
W
T
P
T
N
K
K
P
H
K
A
R
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
13.3
100
N.A.
100
0
N.A.
13.3
0
0
0
N.A.
13.3
N.A.
0
0
P-Site Similarity:
100
100
13.3
100
N.A.
100
13.3
N.A.
20
0
0
0
N.A.
26.6
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
15
8
8
29
0
0
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
8
0
29
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
15
0
29
0
0
0
0
% D
% Glu:
8
0
29
8
0
0
0
0
0
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
8
8
0
8
0
29
0
8
0
8
8
0
36
0
8
% I
% Lys:
15
15
8
29
36
0
8
0
15
8
8
0
22
15
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
36
0
% N
% Pro:
29
0
8
0
0
8
0
0
0
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
8
0
15
8
36
36
0
36
0
15
0
0
29
% S
% Thr:
0
29
8
0
8
0
15
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _