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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
19.7
Human Site:
S557
Identified Species:
33.33
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
S557
V
E
E
S
Y
L
P
S
P
D
V
L
K
G
K
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
S746
V
E
E
S
Y
L
P
S
P
D
V
L
K
G
K
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
M500
S
I
K
Q
Q
K
V
M
V
Q
H
M
K
K
L
Dog
Lupus familis
XP_542772
1140
126851
S561
V
E
E
S
Y
L
P
S
P
D
V
L
K
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
S558
M
E
E
S
Y
L
P
S
P
D
V
L
K
G
K
Rat
Rattus norvegicus
Q62688
1096
122754
S530
S
S
E
S
Y
L
P
S
P
E
K
L
K
H
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
S517
E
D
E
G
A
E
M
S
Q
R
V
G
K
E
G
Chicken
Gallus gallus
Q2VRL0
637
72514
K104
F
L
K
K
E
Q
F
K
T
E
G
A
E
T
T
Frog
Xenopus laevis
Q32NH8
758
87399
L225
D
G
K
K
L
T
L
L
E
F
V
D
F
L
Q
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
E251
G
C
V
L
T
T
L
E
L
R
D
F
L
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
P548
G
S
T
T
N
V
H
P
W
L
S
S
M
V
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
D525
S
G
E
V
S
E
E
D
D
S
L
A
S
T
T
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
T119
I
Y
H
G
H
T
L
T
S
K
I
L
F
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
H336
Q
F
L
I
T
E
Q
H
E
Q
V
D
R
Q
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
60
N.A.
26.6
0
6.6
6.6
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
66.6
N.A.
33.3
20
20
6.6
N.A.
13.3
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
15
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
8
8
29
8
15
0
0
8
% D
% Glu:
8
29
50
0
8
22
8
8
15
15
0
0
8
8
0
% E
% Phe:
8
8
0
0
0
0
8
0
0
8
0
8
15
0
0
% F
% Gly:
15
15
0
15
0
0
0
0
0
0
8
8
0
36
8
% G
% His:
0
0
8
0
8
0
8
8
0
0
8
0
0
8
0
% H
% Ile:
8
8
0
8
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
22
15
0
8
0
8
0
8
8
0
50
15
22
% K
% Leu:
0
8
8
8
8
36
22
8
8
8
8
43
8
8
8
% L
% Met:
8
0
0
0
0
0
8
8
0
0
0
8
8
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
36
8
36
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
8
8
8
0
8
15
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
15
0
0
8
0
8
% R
% Ser:
22
15
0
36
8
0
0
43
8
8
8
8
8
0
0
% S
% Thr:
0
0
8
8
15
22
0
8
8
0
0
0
0
15
22
% T
% Val:
22
0
8
8
0
8
8
0
8
0
50
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
36
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _