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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
17.58
Human Site:
S577
Identified Species:
29.74
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
S577
K
K
L
S
S
N
C
S
G
V
E
G
D
V
T
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
S766
K
K
L
S
S
N
C
S
G
V
E
G
D
V
T
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
V519
L
Y
T
T
S
P
N
V
E
E
S
Y
L
P
S
Dog
Lupus familis
XP_542772
1140
126851
S581
K
K
L
S
S
N
C
S
G
V
E
G
D
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
S578
K
K
L
S
S
N
C
S
G
V
E
G
D
V
T
Rat
Rattus norvegicus
Q62688
1096
122754
D550
K
K
L
P
S
E
S
D
L
L
E
G
E
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
F536
N
I
V
P
V
K
R
F
Q
L
C
K
D
L
S
Chicken
Gallus gallus
Q2VRL0
637
72514
D123
I
L
K
Y
E
P
I
D
E
V
R
K
R
R
Q
Frog
Xenopus laevis
Q32NH8
758
87399
I244
E
E
E
N
T
E
E
I
A
M
D
L
I
A
R
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S270
A
S
L
V
H
A
K
S
L
I
Q
T
F
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
A568
K
F
Q
G
F
D
K
A
I
E
K
N
I
A
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
S546
I
Q
L
C
K
E
L
S
D
L
V
P
V
F
F
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
T138
I
N
Q
H
A
F
E
T
S
E
Y
P
V
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
T355
F
I
K
Y
R
E
P
T
Q
L
T
M
G
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
6.6
100
N.A.
100
53.3
N.A.
6.6
6.6
0
13.3
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
20
100
N.A.
100
66.6
N.A.
33.3
6.6
40
26.6
N.A.
26.6
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
0
8
8
0
0
0
0
15
0
% A
% Cys:
0
0
0
8
0
0
29
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
15
8
0
8
0
36
0
8
% D
% Glu:
8
8
8
0
8
29
15
0
15
22
36
0
8
8
0
% E
% Phe:
8
8
0
0
8
8
0
8
0
0
0
0
8
8
8
% F
% Gly:
0
0
0
8
0
0
0
0
29
0
0
36
8
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
22
15
0
0
0
0
8
8
8
8
0
0
15
8
0
% I
% Lys:
43
36
15
0
8
8
15
0
0
0
8
15
0
0
0
% K
% Leu:
8
8
50
0
0
0
8
0
15
29
0
8
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
8
8
0
8
0
29
8
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
15
0
15
8
0
0
0
0
15
0
8
0
% P
% Gln:
0
8
15
0
0
0
0
0
15
0
8
0
0
8
8
% Q
% Arg:
0
0
0
0
8
0
8
0
0
0
8
0
8
8
8
% R
% Ser:
0
8
0
29
43
0
8
43
8
0
8
0
0
0
15
% S
% Thr:
0
0
8
8
8
0
0
15
0
0
8
8
0
0
36
% T
% Val:
0
0
8
8
8
0
0
8
0
36
8
0
15
36
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
15
0
0
0
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _