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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
18.79
Human Site:
S752
Identified Species:
31.79
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
S752
K
D
S
V
P
G
V
S
P
Q
L
L
H
I
K
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
S941
K
D
S
V
P
G
V
S
P
Q
L
L
H
I
K
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
N672
G
C
Q
I
V
A
M
N
F
Q
T
P
G
L
M
Dog
Lupus familis
XP_542772
1140
126851
S756
K
D
S
V
P
G
V
S
P
Q
L
L
H
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
S753
K
D
S
V
P
G
V
S
P
Q
L
L
H
I
K
Rat
Rattus norvegicus
Q62688
1096
122754
S720
K
G
I
V
P
G
V
S
P
L
L
L
H
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
N689
I
K
I
I
S
G
Q
N
F
P
K
P
K
G
S
Chicken
Gallus gallus
Q2VRL0
637
72514
T276
I
L
G
D
K
L
L
T
S
P
I
G
D
I
E
Frog
Xenopus laevis
Q32NH8
758
87399
Q397
E
Q
Q
D
A
M
A
Q
H
L
K
S
I
L
G
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Q423
A
I
M
A
Q
Q
L
Q
S
I
L
G
K
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
K721
L
P
S
D
T
V
K
K
E
F
R
T
R
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
A701
P
R
P
R
G
S
N
A
K
G
D
S
A
D
P
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
K291
E
D
Y
V
S
H
N
K
R
Y
L
S
R
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
P508
R
T
D
K
L
P
S
P
R
E
L
K
H
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
6.6
100
N.A.
100
80
N.A.
6.6
6.6
0
6.6
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
100
33.3
100
N.A.
100
80
N.A.
20
33.3
13.3
13.3
N.A.
13.3
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
8
8
8
0
0
0
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
36
8
22
0
0
0
0
0
0
8
0
8
8
0
% D
% Glu:
15
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% F
% Gly:
8
8
8
0
8
43
0
0
0
8
0
15
8
8
8
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
43
0
0
% H
% Ile:
15
8
15
15
0
0
0
0
0
8
8
0
8
43
8
% I
% Lys:
36
8
0
8
8
0
8
15
8
0
15
8
15
15
36
% K
% Leu:
8
8
0
0
8
8
15
0
0
15
58
36
0
22
8
% L
% Met:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
15
15
0
0
0
0
0
0
0
% N
% Pro:
8
8
8
0
36
8
0
8
36
15
0
15
0
0
8
% P
% Gln:
0
8
15
0
8
8
8
15
0
36
0
0
0
0
0
% Q
% Arg:
8
8
0
8
0
0
0
0
15
0
8
0
15
0
0
% R
% Ser:
0
0
36
0
15
8
8
36
15
0
0
22
0
0
8
% S
% Thr:
0
8
0
0
8
0
0
8
0
0
8
8
0
0
0
% T
% Val:
0
0
0
43
8
8
36
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _