KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
17.27
Human Site:
T545
Identified Species:
29.23
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
T545
L
L
G
D
K
L
Y
T
T
S
P
N
V
E
E
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
T734
L
L
G
D
K
L
Y
T
T
S
P
N
V
E
E
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
L488
E
Y
P
L
I
L
C
L
E
N
H
C
S
I
K
Dog
Lupus familis
XP_542772
1140
126851
T549
I
L
G
D
K
L
Y
T
T
L
P
N
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
T546
I
L
G
D
K
L
Y
T
T
S
P
N
M
E
E
Rat
Rattus norvegicus
Q62688
1096
122754
T518
V
F
G
N
K
L
Y
T
E
A
P
L
S
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
G505
T
T
C
P
G
L
E
G
D
V
T
D
E
D
E
Chicken
Gallus gallus
Q2VRL0
637
72514
T92
N
R
K
N
L
A
D
T
E
L
T
A
F
L
K
Frog
Xenopus laevis
Q32NH8
758
87399
Q213
D
E
V
L
K
I
F
Q
D
F
S
K
D
G
K
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
H239
E
L
D
A
V
F
R
H
Y
S
G
N
G
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
A536
G
A
E
A
E
A
A
A
A
N
Y
S
G
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
N513
I
V
G
K
K
L
D
N
P
D
T
D
S
G
E
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
N107
L
D
V
W
D
G
A
N
D
E
P
I
I
Y
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
F324
P
P
H
S
H
L
S
F
E
N
F
F
Q
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
46.6
N.A.
13.3
6.6
6.6
20
N.A.
0
N.A.
26.6
13.3
P-Site Similarity:
100
100
20
93.3
N.A.
100
66.6
N.A.
26.6
20
26.6
20
N.A.
20
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
15
0
15
15
8
8
8
0
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
8
0
0
0
0
8
0
8
0
% C
% Asp:
8
8
8
29
8
0
15
0
22
8
0
15
8
8
0
% D
% Glu:
15
8
8
0
8
0
8
0
29
8
0
0
8
29
50
% E
% Phe:
0
8
0
0
0
8
8
8
0
8
8
8
8
8
0
% F
% Gly:
8
0
43
0
8
8
0
8
0
0
8
0
15
15
0
% G
% His:
0
0
8
0
8
0
0
8
0
0
8
0
0
0
8
% H
% Ile:
22
0
0
0
8
8
0
0
0
0
0
8
8
8
0
% I
% Lys:
0
0
8
8
50
0
0
0
0
0
0
8
0
0
22
% K
% Leu:
22
36
0
15
8
65
0
8
0
15
0
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
15
0
0
0
15
0
22
0
36
0
0
0
% N
% Pro:
8
8
8
8
0
0
0
0
8
0
43
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
8
0
0
29
8
8
22
15
0
% S
% Thr:
8
8
0
0
0
0
0
43
29
0
22
0
0
0
8
% T
% Val:
8
8
15
0
8
0
0
0
0
8
0
0
22
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
36
0
8
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _