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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
19.09
Human Site:
T986
Identified Species:
32.31
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
T986
N
L
S
E
Q
Y
P
T
M
E
L
Q
G
I
V
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
T1175
N
L
S
E
Q
Y
P
T
M
E
L
Q
G
I
V
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
D898
N
A
Q
P
P
I
R
D
A
T
D
L
R
E
N
Dog
Lupus familis
XP_542772
1140
126851
T999
N
L
S
E
Q
Y
P
T
M
E
L
Q
G
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
T987
N
L
S
E
P
Y
P
T
M
E
L
Q
A
I
V
Rat
Rattus norvegicus
Q62688
1096
122754
Y954
V
M
K
D
C
F
P
Y
L
E
P
L
G
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
G915
F
P
T
M
E
L
Q
G
T
V
P
E
V
L
K
Chicken
Gallus gallus
Q2VRL0
637
72514
H502
R
N
S
T
F
N
P
H
N
V
G
R
Y
S
N
Frog
Xenopus laevis
Q32NH8
758
87399
N623
T
E
G
Y
S
P
V
N
L
S
I
L
V
I
S
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S649
Q
L
T
I
R
V
I
S
A
Q
Q
L
P
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
A949
K
Q
W
T
D
M
I
A
R
H
R
K
E
E
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
P929
D
S
D
E
H
G
Y
P
A
I
V
T
M
G
T
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
E517
C
A
M
I
G
F
K
E
S
C
G
L
A
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
T734
E
N
G
S
D
P
V
T
V
K
I
R
I
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
6.6
100
N.A.
86.6
20
N.A.
0
13.3
6.6
6.6
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
6.6
100
N.A.
86.6
53.3
N.A.
26.6
20
20
40
N.A.
6.6
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
8
22
0
0
0
15
0
0
% A
% Cys:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
8
8
15
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
8
8
0
36
8
0
0
8
0
36
0
8
8
15
0
% E
% Phe:
8
0
0
0
8
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
0
8
8
0
8
0
0
15
0
29
8
0
% G
% His:
0
0
0
0
8
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
8
15
0
0
8
15
0
8
36
15
% I
% Lys:
8
0
8
0
0
0
8
0
0
8
0
8
0
8
8
% K
% Leu:
0
36
0
0
0
8
0
0
15
0
29
36
0
15
0
% L
% Met:
0
8
8
8
0
8
0
0
29
0
0
0
8
0
8
% M
% Asn:
36
15
0
0
0
8
0
8
8
0
0
0
0
0
15
% N
% Pro:
0
8
0
8
15
15
43
8
0
0
15
0
8
0
0
% P
% Gln:
8
8
8
0
22
0
8
0
0
8
8
29
0
0
0
% Q
% Arg:
8
0
0
0
8
0
8
0
8
0
8
15
8
0
0
% R
% Ser:
0
8
36
8
8
0
0
8
8
8
0
0
0
15
15
% S
% Thr:
8
0
15
15
0
0
0
36
8
8
0
8
0
8
8
% T
% Val:
8
0
0
0
0
8
15
0
8
15
8
0
15
0
29
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
0
29
8
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _