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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
20.91
Human Site:
Y1004
Identified Species:
35.38
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
Y1004
L
K
K
I
V
T
T
Y
D
M
M
I
Q
S
L
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
Y1193
L
K
K
I
V
T
T
Y
D
M
M
I
Q
S
L
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
E915
N
A
V
V
S
F
K
E
L
C
G
L
S
S
V
Dog
Lupus familis
XP_542772
1140
126851
Y1017
L
K
K
I
V
T
T
Y
D
M
M
I
Q
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
Y1005
L
K
K
I
V
T
T
Y
D
M
M
M
Q
S
L
Rat
Rattus norvegicus
Q62688
1096
122754
Y972
Q
K
R
M
L
A
A
Y
D
L
M
I
Q
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
I932
V
T
A
F
D
T
M
I
Q
T
I
K
T
L
I
Chicken
Gallus gallus
Q2VRL0
637
72514
S519
S
L
S
I
R
L
I
S
G
H
Q
L
P
P
S
Frog
Xenopus laevis
Q32NH8
758
87399
S640
Q
L
P
K
V
E
N
S
K
E
G
S
I
V
D
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
D666
D
K
P
N
S
I
V
D
P
Q
V
W
V
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
S966
L
R
Q
H
V
Q
D
S
Q
D
A
M
K
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
K949
Q
R
S
F
N
K
L
K
N
L
I
A
H
C
V
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
L534
L
K
Q
C
V
R
S
L
F
N
R
L
A
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
T751
L
L
P
R
L
N
D
T
S
P
S
R
N
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
6.6
100
N.A.
93.3
40
N.A.
6.6
6.6
6.6
6.6
N.A.
20
N.A.
0
20
P-Site Similarity:
100
100
26.6
100
N.A.
100
66.6
N.A.
26.6
13.3
6.6
20
N.A.
53.3
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
8
0
0
0
8
8
8
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% C
% Asp:
8
0
0
0
8
0
15
8
36
8
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
8
0
8
0
8
0
0
0
15
0
% E
% Phe:
0
0
0
15
0
8
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
15
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
36
0
8
8
8
0
0
15
29
8
0
15
% I
% Lys:
0
50
29
8
0
8
8
8
8
0
0
8
8
8
0
% K
% Leu:
50
22
0
0
15
8
8
8
8
15
0
22
0
8
36
% L
% Met:
0
0
0
8
0
0
8
0
0
29
36
15
0
0
0
% M
% Asn:
8
0
0
8
8
8
8
0
8
8
0
0
8
8
0
% N
% Pro:
0
0
22
0
0
0
0
0
8
8
0
0
8
8
0
% P
% Gln:
22
0
15
0
0
8
0
0
15
8
8
0
36
0
0
% Q
% Arg:
0
15
8
8
8
8
0
0
0
0
8
8
0
0
0
% R
% Ser:
8
0
15
0
15
0
8
22
8
0
8
8
8
36
15
% S
% Thr:
0
8
0
0
0
36
29
8
0
8
0
0
8
0
15
% T
% Val:
8
0
8
8
50
0
8
0
0
0
8
0
8
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _