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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
20.3
Human Site:
Y459
Identified Species:
34.36
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
Y459
G
P
S
D
I
T
G
Y
I
R
A
L
K
M
G
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
Y648
G
P
S
D
I
T
G
Y
I
R
A
L
K
M
G
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
S408
L
S
H
Y
F
I
N
S
S
H
N
T
Y
L
I
Dog
Lupus familis
XP_542772
1140
126851
Y463
G
P
S
D
I
T
G
Y
I
R
A
L
K
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
Y460
G
P
S
D
I
T
G
Y
I
R
A
L
K
M
G
Rat
Rattus norvegicus
Q62688
1096
122754
Y432
G
P
A
D
I
N
G
Y
V
R
A
L
K
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
D425
I
V
F
R
S
V
I
D
I
I
N
K
Y
A
F
Chicken
Gallus gallus
Q2VRL0
637
72514
Q12
R
W
F
L
N
I
I
Q
D
G
F
M
N
G
K
Frog
Xenopus laevis
Q32NH8
758
87399
D133
V
T
N
M
D
R
K
D
L
M
D
Q
W
I
C
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
K159
S
N
M
S
Q
K
E
K
L
D
H
W
I
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
P453
H
P
L
D
P
G
L
P
L
P
P
P
C
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
S432
A
T
S
K
I
T
I
S
S
A
L
R
I
I
R
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
Y27
E
E
G
R
Q
R
G
Y
L
G
I
D
G
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
K244
W
Q
I
T
V
S
E
K
E
E
D
E
K
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
0
100
N.A.
100
80
N.A.
6.6
0
0
6.6
N.A.
13.3
N.A.
20
13.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
93.3
N.A.
6.6
6.6
20
13.3
N.A.
20
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
8
36
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
0
0
0
43
8
0
0
15
8
8
15
8
0
0
8
% D
% Glu:
8
8
0
0
0
0
15
0
8
8
0
8
0
0
0
% E
% Phe:
0
0
15
0
8
0
0
0
0
0
8
0
0
8
8
% F
% Gly:
36
0
8
0
0
8
43
0
0
15
0
0
8
8
43
% G
% His:
8
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
8
0
8
0
43
15
22
0
36
8
8
0
15
15
8
% I
% Lys:
0
0
0
8
0
8
8
15
0
0
0
8
43
15
8
% K
% Leu:
8
0
8
8
0
0
8
0
29
0
8
36
0
8
8
% L
% Met:
0
0
8
8
0
0
0
0
0
8
0
8
0
36
0
% M
% Asn:
0
8
8
0
8
8
8
0
0
0
15
0
8
0
0
% N
% Pro:
0
43
0
0
8
0
0
8
0
8
8
8
0
0
0
% P
% Gln:
0
8
0
0
15
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
8
0
0
15
0
15
0
0
0
36
0
8
0
8
8
% R
% Ser:
8
8
36
8
8
8
0
15
15
0
0
0
0
0
0
% S
% Thr:
0
15
0
8
0
36
0
0
0
0
0
8
0
0
8
% T
% Val:
8
8
0
0
8
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% W
% Tyr:
0
0
0
8
0
0
0
43
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _