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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL2
All Species:
18.18
Human Site:
Y667
Identified Species:
30.77
UniProt:
Q9UPR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPR0
NP_001137854.1
1127
125866
Y667
N
P
G
D
F
V
N
Y
N
K
R
F
L
A
R
Chimpanzee
Pan troglodytes
XP_526146
1316
145538
Y856
N
P
G
D
F
V
N
Y
N
K
R
F
L
A
R
Rhesus Macaque
Macaca mulatta
XP_001084228
1034
116313
Q598
V
S
I
C
K
S
V
Q
F
K
E
F
Q
V
S
Dog
Lupus familis
XP_542772
1140
126851
Y671
N
P
G
D
F
V
N
Y
N
K
R
F
L
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K394
1128
125754
Y668
N
P
G
D
F
V
N
Y
N
K
R
F
L
A
R
Rat
Rattus norvegicus
Q62688
1096
122754
Y635
Y
P
E
D
F
V
N
Y
N
K
K
F
L
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
D615
S
S
N
M
N
P
Q
D
F
W
K
C
G
C
Q
Chicken
Gallus gallus
Q2VRL0
637
72514
E202
L
K
G
C
R
C
L
E
I
D
C
W
D
G
S
Frog
Xenopus laevis
Q32NH8
758
87399
Y323
G
Q
S
S
I
E
G
Y
I
R
A
L
K
R
G
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
A349
S
T
E
P
Y
I
R
A
L
N
Q
G
C
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
Q647
D
L
P
M
Q
L
N
Q
G
K
F
E
Y
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
N627
N
P
Q
E
F
W
N
N
G
V
Q
M
V
C
L
Sea Urchin
Strong. purpuratus
XP_797105
652
73813
G217
E
V
T
D
E
D
E
G
S
D
T
D
R
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
G434
D
I
W
D
G
E
N
G
P
V
V
C
H
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
86.5
97
N.A.
96.7
62.5
N.A.
85.5
23.2
27.8
27
N.A.
20.5
N.A.
38.3
34.4
Protein Similarity:
100
85.6
87.2
97.8
N.A.
98.2
76.4
N.A.
89.1
35.8
41.9
42.4
N.A.
40
N.A.
58
45.3
P-Site Identity:
100
100
13.3
100
N.A.
100
73.3
N.A.
0
6.6
6.6
0
N.A.
13.3
N.A.
26.6
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
86.6
N.A.
20
13.3
13.3
26.6
N.A.
26.6
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
0
29
0
% A
% Cys:
0
0
0
15
0
8
0
0
0
0
8
15
8
15
8
% C
% Asp:
15
0
0
50
0
8
0
8
0
15
0
8
8
0
0
% D
% Glu:
8
0
15
8
8
15
8
8
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
43
0
0
0
15
0
8
43
0
0
8
% F
% Gly:
8
0
36
0
8
0
8
15
15
0
0
8
8
22
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
8
0
8
8
0
0
15
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
0
0
50
15
0
8
0
8
% K
% Leu:
8
8
0
0
0
8
8
0
8
0
0
8
36
0
8
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
36
0
8
0
8
0
58
8
36
8
0
0
0
8
0
% N
% Pro:
0
43
8
8
0
8
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
8
0
8
15
0
0
15
0
8
0
8
% Q
% Arg:
0
0
0
0
8
0
8
0
0
8
29
0
8
15
36
% R
% Ser:
15
15
8
8
0
8
0
0
8
0
0
0
0
8
15
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
8
8
0
0
0
36
8
0
0
15
8
0
8
8
0
% V
% Trp:
0
0
8
0
0
8
0
0
0
8
0
8
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
43
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _