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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFR2 All Species: 7.58
Human Site: T377 Identified Species: 15.15
UniProt: Q9UPR6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPR6 NP_055989.1 939 101362 T377 P G A E A K P T S P T G P S V
Chimpanzee Pan troglodytes XP_001154962 1029 112351 S396 S S T A V S A S K P T A S P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_854814 917 97952 A368 M C T L S K P A L A K R P A L
Cat Felis silvestris
Mouse Mus musculus O88532 1074 116840 S440 S S T A A S A S K P T A S P S
Rat Rattus norvegicus Q562A2 1073 116800 S438 S S T A V S A S K P T A S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508407 1102 120156 S469 S S T S A S A S K P T A S T S
Chicken Gallus gallus XP_424997 1045 113993 S413 S S T S T S A S K P A A S A S
Frog Xenopus laevis Q6GPM1 1054 115199 S431 T S A V S K A S A T S S S T S
Zebra Danio Brachydanio rerio Q6PCR6 1074 116505 N436 T S S T A A P N K T S S S N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788510 884 96010 N376 K L C D C K F N D P N A K E M
Honey Bee Apis mellifera XP_624428 928 100974 G358 A A A A K T A G A K K P T V T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182008 936 104584 I403 D L D M E K D I L P V G E D Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.7 N.A. 58.7 N.A. 45.9 43.7 N.A. 43.8 46.1 45.1 46.3 N.A. 40.2 44.2 N.A. 42.4
Protein Similarity: 100 58.9 N.A. 69.8 N.A. 58 56.2 N.A. 56.7 58.8 58.5 59.3 N.A. 55.1 57.9 N.A. 57.6
P-Site Identity: 100 13.3 N.A. 20 N.A. 20 13.3 N.A. 20 6.6 13.3 13.3 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 20 N.A. 40 N.A. 26.6 20 N.A. 33.3 20 46.6 40 N.A. 26.6 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 25 34 34 9 59 9 17 9 9 50 0 17 0 % A
% Cys: 0 9 9 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 9 0 0 9 0 9 0 0 0 0 9 0 % D
% Glu: 0 0 0 9 9 0 0 0 0 0 0 0 9 9 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 9 0 0 0 17 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % I
% Lys: 9 0 0 0 9 42 0 0 50 9 17 0 9 0 0 % K
% Leu: 0 17 0 9 0 0 0 0 17 0 0 0 0 0 9 % L
% Met: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 17 0 0 9 0 0 9 0 % N
% Pro: 9 0 0 0 0 0 25 0 0 67 0 9 17 25 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 42 59 9 17 17 42 0 50 9 0 17 17 59 9 50 % S
% Thr: 17 0 50 9 9 9 0 9 0 17 42 0 9 17 9 % T
% Val: 0 0 0 9 17 0 0 0 0 0 9 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _