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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
16.36
Human Site:
S1094
Identified Species:
27.69
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1094
S
E
K
D
E
G
D
S
D
E
E
E
T
V
S
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
E967
A
L
D
S
E
G
E
E
A
S
Q
E
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
S1102
S
E
K
E
E
V
D
S
D
G
E
E
T
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1136
S
E
K
D
N
G
D
S
E
E
E
E
T
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1089
D
K
E
E
E
Q
D
S
E
E
E
D
A
A
S
Frog
Xenopus laevis
Q66J90
1938
216239
S1038
G
K
E
E
D
L
V
S
E
E
E
D
I
T
S
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1020
S
D
D
E
A
S
S
S
S
S
S
K
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
A920
S
S
S
T
S
S
E
A
E
Y
E
A
I
D
C
Honey Bee
Apis mellifera
XP_395451
1406
159180
D686
A
P
S
P
L
P
Q
D
E
D
S
R
Q
S
D
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
Q787
I
R
Q
Q
I
M
R
Q
C
F
A
A
L
D
E
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
R1040
R
P
N
P
M
F
P
R
G
P
P
P
S
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
E593
D
R
R
R
R
D
E
E
A
D
I
E
E
E
K
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
26.6
0
80
N.A.
80
N.A.
N.A.
0
40
26.6
20
N.A.
13.3
0
0
0
P-Site Similarity:
100
53.3
0
86.6
N.A.
86.6
N.A.
N.A.
0
73.3
66.6
46.6
N.A.
33.3
20
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
8
0
0
8
15
0
8
15
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
15
8
15
15
8
8
29
8
15
15
0
15
0
15
8
% D
% Glu:
0
22
15
29
29
0
22
15
36
29
43
36
8
15
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
22
0
0
8
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
8
0
15
0
0
% I
% Lys:
0
15
22
0
0
0
0
0
0
0
0
8
0
0
8
% K
% Leu:
0
8
0
0
8
8
0
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
0
15
0
8
8
0
0
8
8
8
0
0
0
% P
% Gln:
0
0
8
8
0
8
8
8
0
0
8
0
8
0
0
% Q
% Arg:
8
15
8
8
8
0
8
8
0
0
0
8
0
0
0
% R
% Ser:
36
8
15
8
8
15
8
43
8
15
15
0
22
15
50
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
22
8
0
% T
% Val:
0
0
0
0
0
8
8
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _