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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
1.52
Human Site:
S1232
Identified Species:
2.56
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1232
P
P
E
E
P
G
L
S
Q
E
G
A
M
L
L
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
P1087
P
P
R
E
V
P
V
P
T
P
A
P
V
E
V
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
K21
R
V
V
G
I
W
T
K
N
K
E
L
E
L
S
Dog
Lupus familis
XP_543382
1925
209302
K1236
P
P
E
E
P
G
L
K
E
E
G
A
K
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
N1293
P
P
E
E
P
G
P
N
T
Q
G
D
M
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
K92
E
L
E
L
S
V
P
K
F
K
I
D
E
F
Y
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1301
F
F
S
K
S
D
D
S
C
L
E
T
H
V
K
Frog
Xenopus laevis
Q66J90
1938
216239
E1214
E
Y
I
E
L
R
L
E
P
V
P
L
V
P
D
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
A1144
P
S
P
K
G
L
P
A
D
E
L
D
V
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
P1037
L
D
E
N
G
I
E
P
T
I
L
R
K
I
P
Honey Bee
Apis mellifera
XP_395451
1406
159180
T803
Q
R
S
L
D
C
P
T
P
T
G
R
E
T
P
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
A904
S
S
S
S
S
S
A
A
T
S
A
R
V
S
E
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
I1182
N
E
V
L
K
T
V
I
Q
E
M
K
I
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
G710
V
R
K
L
K
S
R
G
V
N
A
R
K
H
G
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
6.6
80
N.A.
66.6
N.A.
N.A.
6.6
6.6
13.3
20
N.A.
6.6
6.6
0
13.3
P-Site Similarity:
100
40
13.3
86.6
N.A.
80
N.A.
N.A.
13.3
20
20
40
N.A.
13.3
13.3
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
15
0
0
22
15
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
8
8
0
8
0
0
22
0
8
8
% D
% Glu:
15
8
36
36
0
0
8
8
8
29
15
0
22
8
8
% E
% Phe:
8
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
15
22
0
8
0
0
29
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
8
0
8
8
0
8
0
8
8
0
8
15
0
% I
% Lys:
0
0
8
15
15
0
0
22
0
15
0
8
22
0
8
% K
% Leu:
8
8
0
29
8
8
22
0
0
8
15
15
0
29
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
15
0
8
% M
% Asn:
8
0
0
8
0
0
0
8
8
8
0
0
0
0
0
% N
% Pro:
36
29
8
0
22
8
29
15
15
8
8
8
0
8
15
% P
% Gln:
8
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% Q
% Arg:
8
15
8
0
0
8
8
0
0
0
0
29
0
0
0
% R
% Ser:
8
15
22
8
22
15
0
15
0
8
0
0
0
8
8
% S
% Thr:
0
0
0
0
0
8
8
8
29
8
0
8
0
8
0
% T
% Val:
8
8
15
0
8
8
15
0
8
8
0
0
29
8
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _