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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
23.33
Human Site:
S1685
Identified Species:
39.49
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1685
Y
H
P
S
T
S
L
S
S
A
K
K
K
K
R
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
T1474
H
H
T
I
T
N
L
T
T
P
K
R
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Y401
F
K
S
A
F
S
P
Y
Q
T
P
V
A
H
F
Dog
Lupus familis
XP_543382
1925
209302
S1687
Y
H
P
S
T
S
L
S
S
A
K
K
K
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1747
Y
H
P
S
T
S
L
S
S
A
K
K
K
K
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
P472
A
E
A
G
S
V
E
P
G
G
T
S
S
F
A
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1770
F
H
P
S
T
S
F
S
T
P
K
K
K
K
R
Frog
Xenopus laevis
Q66J90
1938
216239
Y1700
Y
H
P
P
T
S
V
Y
S
P
K
K
K
K
R
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
T1608
P
T
N
M
G
S
A
T
G
V
K
K
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
G1417
T
G
C
A
R
T
E
G
F
Y
K
L
D
V
R
Honey Bee
Apis mellifera
XP_395451
1406
159180
R1183
G
Y
Y
K
V
D
V
R
E
K
A
K
H
K
H
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
I1284
D
E
E
L
D
G
V
I
P
V
A
A
G
C
S
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
P1724
L
T
A
C
P
D
P
P
Q
P
K
R
K
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
H1090
E
K
S
K
Y
L
P
H
H
I
K
V
K
K
A
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
40
6.6
100
N.A.
100
N.A.
N.A.
0
73.3
73.3
26.6
N.A.
13.3
13.3
0
20
P-Site Similarity:
100
80
20
100
N.A.
100
N.A.
N.A.
6.6
86.6
80
46.6
N.A.
26.6
26.6
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
15
0
0
8
0
0
22
15
8
8
0
15
% A
% Cys:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
8
15
0
0
0
0
0
0
8
0
0
% D
% Glu:
8
15
8
0
0
0
15
0
8
0
0
0
0
0
0
% E
% Phe:
15
0
0
0
8
0
8
0
8
0
0
0
0
8
8
% F
% Gly:
8
8
0
8
8
8
0
8
15
8
0
0
8
0
0
% G
% His:
8
43
0
0
0
0
0
8
8
0
0
0
8
8
8
% H
% Ile:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
0
15
0
15
0
0
0
0
0
8
72
50
65
58
8
% K
% Leu:
8
0
0
8
0
8
29
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
36
8
8
0
22
15
8
29
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
15
0
15
50
% R
% Ser:
0
0
15
29
8
50
0
29
29
0
0
8
8
0
8
% S
% Thr:
8
15
8
0
43
8
0
15
15
8
8
0
0
0
0
% T
% Val:
0
0
0
0
8
8
22
0
0
15
0
15
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
29
8
8
0
8
0
0
15
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _