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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETD1B All Species: 20.91
Human Site: T1682 Identified Species: 35.38
UniProt: Q9UPS6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPS6 NP_055863.1 1923 208732 T1682 L W V Y H P S T S L S S A K K
Chimpanzee Pan troglodytes XP_523492 1707 185692 T1471 H W V H H T I T N L T T P K R
Rhesus Macaque Macaca mulatta XP_001092031 624 66545 F398 A P G F K S A F S P Y Q T P V
Dog Lupus familis XP_543382 1925 209302 T1684 L W V Y H P S T S L S S A K K
Cat Felis silvestris
Mouse Mus musculus Q8CFT2 1985 215333 T1744 L W V Y H P S T S L S S A K K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510235 695 75024 S469 A P A A E A G S V E P G G T S
Chicken Gallus gallus Q5F3P8 2008 223067 T1767 L W V F H P S T S F S T P K K
Frog Xenopus laevis Q66J90 1938 216239 T1697 L W V Y H P P T S V Y S P K K
Zebra Danio Brachydanio rerio Q1LY77 1844 204122 G1605 H H P P T N M G S A T G V K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001015221 1641 188364 R1414 R H K T G C A R T E G F Y K L
Honey Bee Apis mellifera XP_395451 1406 159180 V1180 R T E G Y Y K V D V R E K A K
Nematode Worm Caenorhab. elegans Q18221 1507 171664 D1281 F Y E D E E L D G V I P V A A
Sea Urchin Strong. purpuratus XP_791552 1963 220543 P1721 P S I L T A C P D P P Q P K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q8X0S9 1313 145607 Y1087 L N S E K S K Y L P H H I K V
Conservation
Percent
Protein Identity: 100 37.3 27.9 91.9 N.A. 87.7 N.A. N.A. 23.1 61.5 55 51 N.A. 24.7 23.9 22.3 21.3
Protein Similarity: 100 50.3 28.8 93.9 N.A. 90.2 N.A. N.A. 26.7 71.1 66.6 63.6 N.A. 39.4 38.6 35.2 35.2
P-Site Identity: 100 40 6.6 100 N.A. 100 N.A. N.A. 0 73.3 73.3 20 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 73.3 20 100 N.A. 100 N.A. N.A. 6.6 86.6 80 26.6 N.A. 20 20 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.2
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.4
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 8 8 0 15 15 0 0 8 0 0 22 15 8 % A
% Cys: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 8 15 0 0 0 0 0 0 % D
% Glu: 0 0 15 8 15 8 0 0 0 15 0 8 0 0 0 % E
% Phe: 8 0 0 15 0 0 0 8 0 8 0 8 0 0 0 % F
% Gly: 0 0 8 8 8 0 8 8 8 0 8 15 8 0 0 % G
% His: 15 15 0 8 43 0 0 0 0 0 8 8 0 0 0 % H
% Ile: 0 0 8 0 0 0 8 0 0 0 8 0 8 0 0 % I
% Lys: 0 0 8 0 15 0 15 0 0 0 0 0 8 72 50 % K
% Leu: 43 0 0 8 0 0 8 0 8 29 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 8 0 0 8 0 0 0 0 0 0 % N
% Pro: 8 15 8 8 0 36 8 8 0 22 15 8 29 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % Q
% Arg: 15 0 0 0 0 0 0 8 0 0 8 0 0 0 15 % R
% Ser: 0 8 8 0 0 15 29 8 50 0 29 29 0 0 8 % S
% Thr: 0 8 0 8 15 8 0 43 8 0 15 15 8 8 0 % T
% Val: 0 0 43 0 0 0 0 8 8 22 0 0 15 0 15 % V
% Trp: 0 43 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 29 8 8 0 8 0 0 15 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _