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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
20.61
Human Site:
T909
Identified Species:
34.87
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T909
R
M
A
K
A
S
L
T
P
V
K
S
G
E
H
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
Q800
R
V
L
A
M
L
V
Q
E
M
K
S
I
M
Q
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
T912
R
M
A
K
A
S
L
T
P
V
K
S
G
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
T900
R
M
A
K
A
S
L
T
P
V
K
S
G
E
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Chicken
Gallus gallus
Q5F3P8
2008
223067
T894
R
L
A
K
A
S
L
T
P
V
K
S
G
G
E
Frog
Xenopus laevis
Q66J90
1938
216239
T858
R
L
A
K
Q
S
L
T
P
V
K
S
G
E
S
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
T839
L
S
A
K
A
T
L
T
P
V
K
T
G
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
F755
E
I
T
A
F
K
H
F
E
T
W
W
D
E
H
Honey Bee
Apis mellifera
XP_395451
1406
159180
G521
A
Q
Y
P
Y
P
Y
G
T
T
Y
L
Q
S
H
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
N622
P
T
F
K
P
I
T
N
A
P
L
P
T
P
Y
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
D861
P
V
H
H
P
R
L
D
H
L
K
P
S
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
P428
P
R
A
G
E
V
I
P
G
P
P
P
T
A
P
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
0
100
N.A.
100
N.A.
N.A.
0
80
80
66.6
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
40
0
100
N.A.
100
N.A.
N.A.
0
86.6
86.6
80
N.A.
20
6.6
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
50
15
36
0
0
0
8
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
15
0
0
0
0
43
8
% E
% Phe:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
8
0
0
0
43
8
8
% G
% His:
0
0
8
8
0
0
8
0
8
0
0
0
0
0
36
% H
% Ile:
0
8
0
0
0
8
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
50
0
8
0
0
0
0
58
0
0
0
0
% K
% Leu:
8
15
8
0
0
8
50
0
0
8
8
8
0
0
0
% L
% Met:
0
22
0
0
8
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
22
0
0
8
15
8
0
8
43
15
8
22
0
8
8
% P
% Gln:
0
8
0
0
8
0
0
8
0
0
0
0
8
0
8
% Q
% Arg:
43
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
36
0
0
0
0
0
43
8
8
8
% S
% Thr:
0
8
8
0
0
8
8
43
8
15
0
8
15
0
0
% T
% Val:
0
15
0
0
0
8
8
0
0
43
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% W
% Tyr:
0
0
8
0
8
0
8
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _